Hub : Genes

CISD1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.0550 0.0230 1.6e-03 0.012 0.020 0.009 0.022 0.009 1.2e-02 1.5e-03 2.2e-02 8.4e-04 2.5e-02
2 GTEx Adipose Subcutaneous 0.1500 0.0400 1.8e-08 0.126 NA 0.093 NA 0.112 1.9e-10 NA 4.8e-08 NA 2.1e-09
3 GTEx Adipose Visceral Omentum 0.1350 0.0490 5.0e-04 0.079 NA 0.045 NA 0.065 6.6e-05 NA 2.2e-03 NA 2.9e-04
4 GTEx Artery Aorta 0.1020 0.0410 9.7e-04 0.105 NA 0.055 NA 0.079 2.3e-06 NA 5.4e-04 NA 4.1e-05
5 GTEx Artery Tibial 0.0924 0.0341 8.3e-04 0.048 NA 0.047 NA 0.036 1.2e-04 NA 1.3e-04 NA 8.2e-04
6 GTEx Breast Mammary Tissue 0.1570 0.0620 1.1e-03 0.009 NA 0.087 NA 0.041 1.0e-01 NA 3.1e-05 NA 3.4e-03
7 GTEx Breast Mammary Tissue (Male) 0.1845 0.0922 2.6e-02 -0.010 NA -0.011 NA -0.012 6.5e-01 NA 7.2e-01 NA 7.5e-01
8 GTEx Breast Mammary Tissue (Female) 0.0554 0.0696 2.4e-01 0.023 NA 0.046 NA 0.005 6.9e-02 NA 1.7e-02 NA 2.1e-01
9 GTEx Colon Transverse 0.1100 0.0460 1.5e-03 0.079 NA 0.021 NA 0.064 1.4e-04 NA 3.5e-02 NA 5.4e-04
10 GTEx Lung 0.0868 0.0336 4.6e-04 0.071 NA 0.045 NA 0.059 4.0e-06 NA 2.3e-04 NA 2.8e-05
11 GTEx Muscle Skeletal 0.0823 0.0321 2.7e-04 0.036 NA 0.055 NA 0.046 1.8e-04 NA 4.4e-06 NA 2.5e-05
12 GTEx Nerve Tibial 0.1490 0.0402 4.1e-08 0.136 NA 0.135 NA 0.132 7.5e-10 NA 8.1e-10 NA 1.4e-09
13 GTEx Testis 0.3220 0.0800 1.1e-08 0.246 NA 0.190 NA 0.213 2.8e-11 NA 7.8e-09 NA 7.6e-10
14 GTEx Thyroid 0.1290 0.0380 2.0e-06 0.105 NA 0.121 NA 0.126 2.0e-08 NA 1.5e-09 NA 7.6e-10
15 GTEx Whole Blood 0.1890 0.0390 8.3e-16 0.180 NA 0.169 NA 0.173 2.2e-16 NA 2.1e-15 NA 1.0e-15
16 METSIM Adipose 0.1167 0.0283 4.4e-16 0.106 0.110 0.110 0.113 0.115 1.3e-15 3.9e-16 4.4e-16 1.6e-16 9.0e-17
17 YFS Blood 0.3453 0.0371 0.0e+00 0.581 0.591 0.598 0.596 0.596 1.7e-240 4.8e-247 6.1e-252 6.0e-251 1.1e-250
18 TCGA Head and Neck Squamous Cell Carcinoma 0.0198 0.0135 7.8e-03 0.012 0.012 0.004 NA 0.007 1.6e-02 1.6e-02 1.1e-01 NA 5.1e-02
19 TCGA Kidney Renal Clear Cell Carcinoma 0.1512 0.0676 2.8e-04 0.047 0.032 0.034 NA 0.041 4.5e-06 1.3e-04 1.0e-04 NA 2.1e-05
20 TCGA Soft Tissue Sarcoma 0.0470 0.0270 8.7e-04 0.006 0.037 0.016 NA 0.010 1.4e-01 2.8e-03 3.8e-02 NA 8.1e-02
21 TCGA Thyroid Carcinoma 0.0750 0.0400 1.8e-03 0.046 0.024 0.032 NA 0.033 2.6e-05 1.9e-03 4.3e-04 NA 3.4e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 2.2 3.5 7.8 -1.8 -2.3 -2.5 -2.4 -1.9 -0.5 0.0 -0.6 -2.8 -2.4 -0.7 -1.3 -2.0 -2.2 -2.3 -2.3 -2.2 1.8 -0.6 -2.2 -0.2
Bipolar Disorder or Schizophrenia 0.7 1.7 3.2 -1.3 -1.4 -1.5 -1.5 -1.1 -0.4 0.0 -0.3 -1.8 -1.5 -1.7 -1.2 -1.4 -1.7 -1.5 -1.8 -1.1 1.1 -0.8 -1.4 -0.7
Depressed Affect (Nagel 2018) 2.7 5.7 9.8 -2.4 -2.7 -2.5 -2.6 -2.2 -2.5 0.0 -1.9 -1.9 -2.5 -3.1 -2.8 -2.7 -2.6 -2.5 -2.7 -2.4 2.4 -1.7 -2.5 -1.8
Depression (Nagel 2018) 0.3 0.5 2.1 -0.5 -0.7 -0.8 -0.8 -0.4 -0.1 0.0 0.1 -1.4 -0.6 -0.6 -0.8 -0.8 -0.6 -0.7 -0.7 -0.7 0.8 -0.3 -0.8 -0.2
Intelligence (Savage-Jansen 2018) 0.1 0.3 1.9 -0.5 0.1 0.1 0.0 1.0 -1.4 0.0 -0.4 0.4 0.2 -1.2 -0.1 -0.0 -0.1 0.1 -0.1 0.2 -0.1 -0.6 0.1 -0.8
Neuroticism (Nagel 2018) 3.9 9.1 14.7 -2.4 -3.6 -3.3 -3.4 -2.7 -3.0 0.0 -2.2 -2.3 -3.2 -3.8 -3.6 -3.5 -3.2 -3.1 -3.3 -3.1 3.0 -2.7 -3.2 -2.7
Schizophrenia (2018) 0.1 0.2 2.5 -0.1 -0.0 0.1 -0.0 0.1 -0.1 0.0 -0.0 0.0 0.0 -1.6 -0.5 -0.1 -0.4 -0.1 -0.4 0.4 -0.1 -0.5 -0.1 -0.7
Schizophrenia vs Biploar Disorder 0.1 0.2 1.4 -0.1 -0.1 0.2 0.0 -0.4 -0.7 0.0 -0.6 0.3 -0.1 -1.2 -0.7 -0.2 -0.2 -0.1 -0.1 0.1 0.2 -0.4 -0.3 -0.6
Worry (Nagel 2018) 5.2 11.0 20.3 -2.6 -4.0 -3.7 -3.8 -2.6 -2.9 0.0 -1.6 -2.3 -3.6 -4.5 -3.9 -3.9 -3.5 -3.6 -3.7 -3.5 3.6 -2.8 -3.6 -2.8
Alzheimer’s Disease (in mother) 3.6 4.2 7.4 2.7 2.3 2.2 2.2 2.0 1.3 0.0 1.3 1.9 2.2 2.7 2.6 2.5 2.1 2.3 2.2 2.1 -2.1 0.5 2.4 0.4
Alzheimer’s Disease (in father) 0.4 0.4 1.7 0.5 0.4 0.3 0.5 0.9 0.6 0.0 1.3 0.1 0.5 0.9 0.9 0.4 0.8 0.7 0.8 0.3 -0.9 -0.1 0.3 -0.1
Alzheimer’s Disease (including proxy) 5.2 7.5 12.5 3.2 3.0 2.9 3.2 3.1 1.9 0.0 2.1 1.8 3.0 2.8 3.5 3.2 3.0 3.3 3.1 3.0 -3.4 0.3 3.0 0.4
Crohns Disease (2017) 6.7 14.7 23.6 2.8 4.5 4.5 4.6 3.5 3.1 0.0 2.4 3.2 4.7 4.2 3.9 4.3 4.9 4.6 4.8 4.0 -4.8 1.2 4.3 0.8
Irritable Bowel Disease (IBD) 6.1 14.6 24.7 2.8 4.6 4.3 4.5 3.1 3.1 0.0 2.1 2.8 4.5 5.0 4.0 4.4 4.8 4.5 4.7 3.8 -4.6 1.9 4.3 1.6
Ulcerative Colitis (UC) 2.7 5.1 10.8 1.7 2.7 2.5 2.6 1.4 2.0 0.0 1.2 1.5 2.6 3.3 2.4 2.7 2.7 2.5 2.6 2.2 -2.5 1.8 2.5 1.7
Major Depression (MDD) 0.1 0.2 0.7 -0.3 0.1 -0.0 -0.0 0.8 0.8 0.0 0.8 -0.3 -0.1 0.1 0.3 -0.2 -0.3 0.1 -0.0 0.3 0.1 0.7 0.2 0.7
Reaction Time 0.1 0.2 0.8 0.2 0.2 0.2 0.2 0.6 -0.0 0.0 -0.8 0.9 0.1 0.9 0.0 0.3 0.0 0.0 0.1 0.2 0.2 0.9 0.3 0.9
Verbal and Numeric Reasoning (VNR) 0.3 0.6 3.1 -0.8 -0.3 -0.2 -0.4 0.9 -1.3 0.0 -0.8 0.9 -0.1 -1.8 -1.1 -0.5 -0.5 -0.4 -0.7 -0.2 0.5 -0.9 -0.5 -1.3
Breast Cancer 1.1 2.6 4.7 -0.1 -2.2 -1.7 -1.8 -0.9 -2.0 0.0 -1.7 0.4 -1.8 -1.2 -1.7 -1.9 -2.1 -2.0 -2.0 -1.7 2.0 -1.3 -1.6 -1.4
Ovarian Cancer 0.5 0.7 2.1 0.1 0.8 1.0 0.9 0.8 1.0 0.0 0.6 1.5 1.0 0.2 0.9 1.0 1.0 0.8 0.7 0.8 -0.9 0.3 0.8 0.4
Prostate Cancer 0.4 0.6 6.8 1.0 0.1 0.2 0.1 -1.2 1.4 0.0 2.6 -0.3 0.1 -0.0 0.2 0.3 0.1 -0.0 0.1 0.3 -0.1 0.4 0.3 0.6
Age at First Birth 0.2 0.3 1.6 -0.1 -0.6 -0.3 -0.4 -0.5 -1.1 0.0 -1.3 0.5 -0.4 -0.5 -0.5 -0.3 -0.2 -0.5 -0.2 -0.4 0.4 -0.5 -0.5 -0.5
Bipolar Disorder (2011) 0.2 0.2 1.2 0.2 0.4 0.2 0.2 -0.3 0.2 0.0 0.2 -0.4 0.3 0.4 0.7 0.5 0.0 0.1 0.0 0.3 -0.9 -1.1 0.4 0.0
Body Mass Index (BMI) (2010) 1.3 1.8 6.0 -2.0 -1.4 -1.6 -1.6 -0.2 -0.7 0.0 -0.4 -2.4 -1.8 -0.9 -1.3 -1.5 -1.4 -1.6 -1.5 -1.5 1.4 -0.5 -1.4 -0.2
Coronary Artery Disease (CAD) 0.3 0.4 2.7 1.6 0.2 0.1 0.5 -0.9 -0.3 0.0 -0.4 0.1 0.2 0.4 0.6 0.1 0.0 0.3 0.4 0.2 -0.6 -1.3 0.3 -1.1
Crohns Disease (2012) 10.5 16.9 26.6 3.9 4.9 4.6 4.8 4.4 3.7 0.0 3.5 2.8 4.8 4.0 4.1 4.4 4.8 4.8 5.0 4.6 -5.2 1.3 4.7 1.1
Mean Putamen Volume 1.3 1.5 2.6 -1.0 -1.4 -1.2 -1.2 -1.0 -1.2 0.0 -1.3 0.0 -1.2 -0.2 -1.6 -1.4 -1.3 -1.3 -1.5 -1.4 1.6 1.4 -1.0 1.4
Fasting Glucose 0.5 0.6 3.0 0.7 0.8 0.6 0.7 1.0 0.7 0.0 1.7 -0.0 0.7 0.9 1.0 0.8 0.7 0.7 0.9 0.7 -0.7 0.2 0.9 0.6
HbA1C 3.9 4.3 7.1 -1.7 -2.7 -2.3 -2.5 -1.8 -1.6 0.0 -1.4 0.0 -2.3 -2.0 -2.4 -2.5 -2.4 -2.7 -2.6 -2.4 2.4 -1.4 -2.3 -1.4
HDL Cholesterol 0.1 0.1 0.7 0.8 -0.0 0.1 0.0 -0.1 -0.1 0.0 0.4 0.8 0.1 -0.0 0.1 0.2 -0.2 -0.0 0.0 0.2 0.3 0.2 0.3 0.4
LDL Cholesterol 0.2 0.3 1.1 1.0 0.4 0.3 0.3 0.9 0.9 0.0 0.9 0.4 0.3 0.0 0.5 0.3 -0.1 0.4 -0.0 0.4 -0.1 0.3 0.7 0.4
Lupus 0.7 1.0 2.7 0.7 1.0 1.1 0.9 1.1 1.6 0.0 1.2 1.5 0.8 1.0 0.9 1.0 0.6 0.7 0.6 1.0 -0.7 1.3 1.2 1.2
Neuroticism (2016) 0.6 0.8 2.1 0.2 -1.1 -1.0 -1.0 -0.2 -0.2 0.0 -0.4 0.0 -1.2 0.0 -1.4 -1.2 -1.2 -1.0 -1.2 -1.4 1.3 0.6 -1.1 0.4
Primary Biliary Cirrhosis 0.1 0.2 1.3 -1.1 0.0 -0.3 -0.3 0.0 0.4 0.0 0.4 -0.3 -0.4 0.4 -0.3 -0.3 -0.3 -0.3 -0.3 -0.6 0.3 0.4 -0.3 0.5
Rheumatoid Arthritis 2.8 3.8 8.0 -2.1 -1.7 -1.9 -1.8 -1.1 -2.3 0.0 -2.0 -2.5 -1.7 -2.1 -2.0 -1.9 -1.8 -1.7 -1.9 -1.9 1.2 -2.8 -2.0 -2.7
Schizophrenia (2014) 0.1 0.3 0.9 0.6 0.6 0.6 0.5 0.6 0.5 0.0 -0.0 -0.3 0.4 -0.6 0.4 0.6 0.2 0.5 0.2 1.0 -0.9 -0.5 0.4 -0.4
Triglycerides 0.2 0.3 1.5 0.1 0.3 0.1 0.2 0.5 -1.2 0.0 -0.8 -0.9 0.2 0.1 1.2 0.3 0.2 0.5 0.4 0.2 -0.7 -0.7 0.5 -0.3
Type 2 Diabetes (T2D) (2012) 1.6 1.8 4.2 1.3 1.1 1.2 1.1 1.7 1.9 0.0 1.6 0.8 1.5 1.7 2.0 1.6 1.1 1.5 1.0 1.4 -1.4 0.6 1.3 0.8
Ulcerative Colitis 2.2 3.2 6.7 1.2 2.2 1.8 2.0 1.7 1.8 0.0 1.2 0.9 2.0 2.6 2.2 2.1 2.1 2.0 2.0 1.7 -2.3 0.4 2.0 0.4
Blood Eosinophil Count 0.7 5.2 10.3 -2.5 -2.5 -2.9 -2.8 -0.4 -0.4 0.0 -0.2 -3.1 -2.9 -1.3 -2.0 -2.8 -2.5 -2.8 -2.6 -3.2 2.8 0.0 -3.0 0.3
Blood Platelet Count 0.1 1.5 5.7 -0.4 -0.8 -0.9 -0.8 1.2 1.8 0.0 2.1 0.2 -0.8 -1.0 -0.9 -0.9 -1.1 -0.8 -1.1 -0.8 1.5 2.4 -0.6 2.4
Blood Red Count 0.1 0.8 2.3 0.7 1.2 0.9 1.0 0.8 1.3 0.0 0.3 0.6 1.1 0.8 1.5 0.9 0.6 1.1 0.8 0.9 -0.8 0.3 1.1 0.3
Blood White Count 0.0 0.3 1.0 -0.4 -0.3 -0.3 -0.4 -0.4 0.3 0.0 -0.6 0.3 -0.2 -0.7 -0.9 -0.5 -0.6 -0.7 -0.7 -0.5 1.0 0.7 -0.3 0.4
Heel T-Score 0.1 1.1 12.6 -1.1 0.7 0.7 0.6 3.5 0.7 0.0 0.0 -0.3 0.6 -0.0 1.8 0.6 0.6 1.2 0.6 0.8 -1.0 0.0 0.4 0.0
BMI 0.3 1.7 3.6 -0.9 -1.6 -1.6 -1.6 -0.9 0.1 0.0 0.0 -1.1 -1.6 0.4 -1.0 -1.6 -1.9 -1.6 -1.6 -1.6 1.9 1.3 -1.2 1.6
Height 0.1 1.8 6.4 -0.8 1.3 1.3 1.2 2.5 1.2 0.0 1.8 1.5 1.3 1.2 1.7 1.2 1.4 1.6 1.4 1.3 -1.1 -0.1 1.0 -0.4
Waist Hip Ratio (WHR) 0.1 0.3 1.2 1.0 0.7 0.4 0.6 -1.1 0.1 0.0 0.4 -0.2 0.6 0.3 1.1 0.7 0.2 0.2 0.3 0.6 -0.4 0.1 0.7 0.1
Systolic Blood Pressure 2.8 14.1 27.7 5.3 4.1 4.0 4.2 2.1 3.1 0.0 2.6 3.2 4.3 4.6 4.2 4.4 4.4 3.9 4.6 4.1 -4.2 0.8 4.3 0.8
Smoking Status 1.7 4.1 6.9 -2.1 -2.2 -2.3 -2.3 -1.9 -1.6 0.0 -2.3 -1.1 -2.4 -0.3 -2.3 -2.3 -2.5 -2.5 -2.6 -2.6 2.5 0.5 -2.1 0.7
Allergy or Eczema 1.5 4.0 10.0 -2.7 -2.2 -2.3 -2.2 -1.2 -0.9 0.0 0.7 -3.2 -2.2 -2.3 -1.3 -2.4 -2.5 -2.2 -2.3 -2.2 2.1 -0.5 -2.2 -0.4
Cardiovascular Disease 0.8 2.6 10.8 3.3 1.4 1.5 1.5 0.6 0.6 0.0 0.2 3.0 1.6 2.2 1.3 1.7 1.4 1.0 1.4 1.4 -0.8 1.8 2.0 1.5
Hypothyroidism (self reported) 0.0 0.1 0.5 -0.3 -0.1 0.1 -0.0 -0.3 -0.6 0.0 -0.7 -0.6 -0.0 -0.6 -0.3 0.1 -0.2 0.1 -0.2 0.1 -0.2 -0.2 0.2 -0.2
Respiratory disease 0.7 1.5 11.8 -0.3 -0.2 -0.2 -0.2 0.7 1.9 0.0 1.8 0.0 -0.5 0.6 0.2 -0.2 -0.4 -0.2 -0.2 -0.2 0.7 3.3 0.3 3.4
Type 2 Diabetes (T2D) (2018) 0.3 0.6 4.0 -1.1 -0.5 -0.4 -0.4 -0.7 -1.1 0.0 -2.0 -0.6 -0.5 0.1 0.1 -0.1 -0.3 -0.2 -0.1 -0.6 -0.1 -1.3 -0.5 -1.2
Lung FEV1/FVC ratio 2.6 13.1 23.2 -1.8 -3.9 -3.9 -4.0 -4.8 -4.4 0.0 -3.2 -3.1 -3.8 -3.3 -4.4 -4.0 -4.4 -4.2 -4.3 -3.7 3.9 -1.8 -3.7 -1.5
Lung FVC 0.0 0.2 0.9 -0.5 -0.5 -0.4 -0.5 1.0 0.3 0.0 0.6 1.0 -0.5 -0.3 0.1 -0.4 -0.1 -0.1 -0.1 -0.1 0.7 -0.0 -0.3 -0.0
Neuroticism 3.5 8.5 19.3 -1.7 -3.3 -2.9 -3.0 -3.2 -3.2 0.0 -2.5 -2.0 -3.0 -4.4 -3.4 -3.2 -3.1 -3.1 -3.2 -2.7 2.8 -2.4 -3.1 -2.5
Chronotype (morning person) 2.8 6.4 13.8 2.7 2.9 2.8 2.8 1.0 3.3 0.0 1.3 1.7 2.8 2.6 3.7 2.9 2.6 2.6 2.7 2.6 -2.6 1.8 3.0 1.8
Hair Pigment 0.0 1.0 3.1 0.3 1.1 1.1 1.1 0.4 1.3 0.0 1.8 1.0 1.2 -0.3 1.2 1.1 1.1 1.0 0.9 1.3 -0.9 -0.3 1.1 -0.3
Tanning 0.1 1.1 4.1 -0.5 1.1 0.8 0.9 2.0 1.2 0.0 1.4 -0.6 0.9 0.7 1.1 1.0 1.2 1.0 1.1 1.0 -1.5 -0.8 0.6 -0.8
Hand grip strength (left) 0.1 0.3 1.0 -0.2 -0.5 -0.7 -0.7 0.4 -0.2 0.0 0.7 -0.8 -0.7 -0.6 -0.2 -0.7 -1.0 -0.6 -0.9 -0.4 0.4 -0.1 -0.3 0.0
Number of treatments/medications taken 1.0 1.8 3.8 -1.2 -1.6 -1.4 -1.6 -1.6 -1.3 0.0 -1.9 -0.8 -1.7 0.3 -1.0 -1.4 -1.5 -1.7 -1.5 -1.9 1.6 0.4 -1.1 0.7
Average weekly spirits intake 2.0 2.4 5.6 2.0 1.4 1.7 1.7 1.1 1.0 0.0 1.0 1.8 1.6 1.5 2.4 1.8 1.6 1.8 1.8 1.6 -1.9 -0.7 1.8 -0.5
Sensitivity / hurt feelings 2.6 4.5 7.2 -1.2 -2.3 -2.3 -2.2 -2.4 -2.6 0.0 -2.6 -1.6 -2.4 -2.0 -2.7 -2.4 -2.3 -2.3 -2.3 -2.2 1.8 -1.4 -2.3 -1.4
Frequency of depressed mood in last 2 weeks 0.5 0.7 1.3 -1.0 -1.0 -0.9 -0.9 -0.7 -0.5 0.0 -1.0 -0.9 -0.8 -1.0 -1.0 -1.0 -0.8 -0.8 -0.9 -1.0 0.9 -0.3 -1.1 -0.3
Hearing difficulty/problems: Yes 0.2 0.3 1.5 0.9 0.5 0.3 0.5 0.8 -0.2 0.0 -0.6 0.3 0.3 1.2 0.6 0.6 0.4 0.6 0.7 0.4 -0.6 -0.4 0.4 -0.4
Relative age of first facial hair 0.3 0.6 1.5 -0.8 -0.7 -0.8 -0.7 -0.4 -0.8 0.0 -0.8 -0.8 -0.8 -1.2 -1.0 -0.9 -0.9 -0.7 -0.9 -0.8 0.8 0.1 -1.1 -0.0
Other serious medical condition/disability diagnosed by doctor 0.5 0.7 5.1 0.1 -0.5 -0.2 -0.2 0.1 1.0 0.0 0.5 0.2 -0.3 1.3 -0.5 -0.2 -0.0 -0.1 -0.0 -0.5 0.5 2.2 0.2 2.3
Ever used hormone-replacement therapy (HRT) 0.4 0.5 2.9 0.4 -0.7 -0.5 -0.5 0.0 -0.1 0.0 0.4 0.5 -0.4 -1.1 -1.7 -0.8 -0.7 -0.5 -0.9 -0.6 0.9 0.5 -0.6 0.1
Ever had hysterectomy (womb removed) 1.4 1.5 5.3 -1.0 -1.2 -1.2 -1.1 -0.4 -0.5 0.0 -0.4 -1.3 -1.2 -0.4 -1.6 -1.2 -0.9 -1.2 -1.1 -1.5 0.7 -2.2 -1.6 -2.3
Systolic blood pressure, automated reading 2.0 5.7 11.4 3.4 2.5 2.6 2.7 1.3 2.0 0.0 1.7 2.3 2.8 2.4 2.7 2.7 2.9 2.5 3.0 2.7 -2.7 0.6 2.7 0.6
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.6 -0.8 -0.3 -0.4 -0.3 0.1 -0.2 0.0 -0.8 0.5 -0.4 0.8 -0.1 -0.3 -0.3 -0.2 -0.2 -0.6 0.0 0.3 -0.3 0.3
Angina 0.4 0.5 1.4 -0.4 -1.0 -0.7 -0.8 -1.1 0.1 0.0 -0.6 0.0 -0.8 0.1 -1.2 -0.7 -0.7 -1.0 -0.7 -0.9 0.7 0.6 -0.7 0.8
Medication for hormone replacement therapy 0.6 0.7 2.2 0.0 -0.7 -0.4 -0.5 -0.9 -1.3 0.0 -1.4 0.2 -0.4 -1.5 -1.4 -0.5 -0.8 -0.7 -0.9 -0.7 0.4 -0.6 -0.6 -0.8
Vitamin and mineral supplements 0.2 0.3 1.1 1.0 -0.3 -0.1 -0.2 0.1 -0.8 0.0 -1.1 0.0 -0.4 0.7 -0.5 -0.1 -0.2 -0.3 -0.1 -0.1 0.2 0.9 0.0 0.9
Supplements: Zinc 0.3 0.3 2.6 -0.8 -0.2 -0.1 -0.1 -1.1 0.1 0.0 0.7 -0.4 0.0 -1.6 0.3 -0.1 0.0 -0.1 -0.1 0.1 -0.1 -0.7 -0.4 -0.6
Medication: Co-codamol 0.8 0.9 2.2 1.3 1.0 0.8 0.9 1.5 1.4 0.0 0.8 0.3 0.6 1.1 1.2 1.0 1.0 1.1 1.0 0.8 -0.9 0.6 1.1 0.7
Medication: Metformin 0.2 0.3 2.2 -0.1 -0.6 -0.4 -0.4 -0.4 -0.8 0.0 -1.5 0.6 -0.4 0.8 0.2 -0.2 -0.5 -0.3 -0.3 -0.6 0.3 -0.1 -0.4 0.1
Diabetes (father) 0.4 0.5 1.3 -0.4 -0.8 -0.6 -0.6 0.1 -1.1 0.0 -0.6 0.5 -0.7 -0.6 -0.9 -0.7 -0.7 -0.6 -0.8 -0.7 0.9 0.9 -0.6 0.8
Diabetes (mother) 0.4 0.5 1.3 -0.8 -0.5 -0.7 -0.7 -1.1 -0.6 0.0 -1.1 -0.4 -0.7 -0.5 -0.7 -0.8 -0.9 -0.8 -0.8 -0.8 0.9 -0.5 -0.7 -0.4
Severe depression (siblings) 0.7 0.8 2.9 1.0 0.7 0.9 0.9 -0.3 0.3 0.0 -0.3 1.7 0.9 1.2 1.0 0.9 1.0 0.9 1.2 0.8 -1.1 0.1 0.9 0.2
Pack years adult smoking proportion 0.6 0.9 2.6 0.9 -1.2 -1.0 -1.0 -0.4 0.4 0.0 -0.5 -0.5 -0.9 -0.7 -1.6 -1.3 -1.3 -1.0 -1.3 -1.1 1.3 -0.4 -1.1 -0.5
Impedance of leg (right) 0.2 0.9 1.9 -0.4 -1.4 -1.1 -1.1 -1.2 -0.1 0.0 -0.6 -0.1 -1.1 -0.8 -0.9 -1.0 -0.8 -1.2 -1.1 -1.4 1.4 0.6 -1.2 0.3
Leg fat-free mass (left) 0.1 0.7 3.0 0.2 1.0 0.8 0.8 1.3 0.5 0.0 0.9 0.7 0.7 1.7 0.9 0.8 0.7 1.0 0.9 0.9 -1.0 0.3 1.0 0.6
Trunk fat percentage 1.0 4.0 6.5 -2.1 -2.4 -2.4 -2.3 -2.6 -1.2 0.0 -1.3 -1.6 -2.3 -0.8 -2.4 -2.5 -2.3 -2.4 -2.2 -2.5 2.1 -0.6 -2.3 -0.4
Hand grip strength (right) 0.2 0.6 1.5 -0.8 -0.9 -1.1 -1.1 -0.0 -0.2 0.0 0.4 -0.9 -1.0 -0.5 -0.6 -1.1 -1.2 -0.9 -1.2 -1.0 0.8 -0.1 -0.8 -0.0
Townsend deprivation index at recruitment 0.2 0.3 2.0 0.3 0.5 -0.0 0.1 -0.4 1.4 0.0 0.8 -1.1 0.0 1.2 -0.2 0.0 0.1 0.0 0.2 -0.1 0.0 0.4 -0.0 0.5
Current tobacco smoking 0.5 0.9 2.8 -1.7 -0.7 -1.0 -0.9 -1.3 -0.3 0.0 -1.1 -1.1 -1.0 -0.6 -0.8 -1.1 -0.9 -1.0 -1.0 -1.1 1.0 -0.1 -1.1 -0.2
Average weekly fortified wine intake 0.1 0.2 0.8 0.4 -0.6 -0.1 -0.2 0.4 -0.4 0.0 -0.9 0.7 -0.2 0.3 -0.2 -0.4 -0.4 -0.1 -0.3 -0.4 0.3 0.2 -0.3 0.2
Maternal smoking around birth 1.3 1.9 5.3 -0.8 -1.6 -1.2 -1.4 -2.3 0.3 0.0 -0.6 -0.4 -1.1 -2.2 -1.7 -1.5 -1.5 -1.7 -1.7 -1.5 1.9 0.6 -1.4 0.2
Fed-up feelings 3.4 6.2 8.7 -1.6 -2.7 -2.7 -2.7 -2.4 -2.8 0.0 -2.7 -1.9 -2.6 -2.9 -2.9 -2.8 -2.8 -2.6 -2.8 -2.5 2.5 -2.2 -2.5 -2.1
Frequency of unenthusiasm / disinterest in last 2 weeks 0.1 0.2 0.7 0.1 -0.2 -0.3 -0.2 -0.8 0.5 0.0 -0.3 -0.8 -0.1 -0.9 -0.6 -0.4 -0.2 -0.3 -0.2 -0.1 0.5 -0.0 -0.4 -0.1
Relative age voice broke 0.2 0.3 1.6 -0.3 -0.4 -0.3 -0.2 -0.2 -0.8 0.0 -0.9 0.7 -0.4 -1.3 -1.0 -0.7 -0.3 -0.1 -0.3 -0.2 0.4 0.6 -0.6 0.4
Taking other prescription medications 3.3 5.1 11.0 -2.8 -2.9 -2.5 -2.8 -1.0 -0.3 0.0 -0.1 -1.4 -3.0 0.3 -2.3 -2.5 -2.5 -2.4 -2.4 -3.0 3.3 2.3 -2.0 2.7
Age when periods started (menarche) 0.4 1.0 3.3 0.2 0.9 1.2 1.1 1.8 0.5 0.0 -0.3 1.4 1.2 0.2 1.5 1.1 0.9 1.2 0.9 1.1 -1.3 -0.6 0.7 -0.8
Bilateral oophorectomy (both ovaries removed) 0.4 0.5 3.0 0.4 0.3 0.5 0.5 0.6 0.5 0.0 0.7 0.4 0.6 0.5 -0.2 0.5 0.8 0.7 0.7 0.4 -0.7 -1.6 0.2 -1.7
Heel bone mineral density (BMD) T-score, automated (left) 1.3 2.9 7.7 0.8 1.7 1.8 1.8 2.8 2.4 0.0 1.8 0.5 1.7 1.1 2.1 1.8 1.7 1.8 1.6 1.9 -2.0 1.0 1.7 1.2
Tinnitus: Yes, but not now, but have in the past 1.1 1.2 5.3 -1.2 -0.9 -1.1 -0.9 -0.3 -0.4 0.0 1.2 -1.9 -0.8 -2.3 -1.3 -1.0 -0.6 -0.8 -0.9 -0.8 0.3 -1.2 -1.2 -1.1
Qualifications: CSEs or equivalent 0.2 0.3 2.3 0.6 -0.1 -0.1 -0.1 -1.5 -0.5 0.0 -0.9 -0.2 -0.0 0.6 0.1 -0.1 -0.2 -0.1 -0.2 -0.2 -0.2 -0.7 -0.2 -0.7
Serious illness, injury or assault to yourself 0.6 0.7 1.7 0.2 -0.9 -1.0 -0.9 -0.7 -0.5 0.0 0.5 -0.7 -0.8 -0.9 -1.3 -0.9 -1.0 -1.1 -1.2 -0.9 1.0 0.5 -0.8 0.5
High blood pressure 0.6 1.7 7.3 2.7 0.8 1.0 0.9 0.4 0.3 0.0 1.2 1.8 1.0 2.1 0.4 1.0 0.9 0.9 1.1 0.9 -0.3 2.2 1.3 2.1
Hayfever, allergic rhinitis or eczema 2.0 4.2 9.5 -2.8 -2.1 -2.2 -2.2 -1.8 -1.1 0.0 0.5 -3.1 -2.2 -2.9 -1.8 -2.3 -2.5 -2.3 -2.4 -2.0 2.0 -0.6 -2.2 -0.5
Multivitamins +/- minerals 0.1 0.2 0.8 -0.6 0.6 0.2 0.3 0.1 0.1 0.0 0.1 -0.6 0.3 -0.3 0.9 0.2 0.1 0.4 0.2 0.3 -0.5 -0.7 0.2 -0.5
Stomach or abdominal pain in last month 0.3 0.4 2.6 0.1 0.6 0.5 0.5 0.5 0.6 0.0 0.0 0.9 0.4 1.6 0.1 0.4 0.4 0.6 0.4 0.2 -0.2 1.3 0.5 1.1
Supplements: Glucosamine 0.5 0.6 2.8 0.2 -0.6 -0.6 -0.6 -0.8 -1.6 0.0 -1.7 -0.9 -0.7 -1.1 -0.2 -0.6 -1.2 -0.4 -0.9 -0.5 0.5 -0.2 -0.4 0.2
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 3.5 -0.1 -0.4 -0.3 -0.4 1.9 0.4 0.0 0.8 0.1 -0.4 0.4 -0.6 -0.3 -0.1 -0.2 -0.3 -0.5 0.4 -0.3 -0.6 -0.5
Medication: Atenolol 0.5 0.6 3.7 0.5 -0.2 -0.0 -0.2 -1.5 0.0 0.0 -0.1 0.9 -0.3 0.3 -0.9 -0.3 -0.3 -0.5 -0.3 -0.3 0.7 1.9 -0.1 1.8
Medication: Levothyroxine sodium 0.4 0.6 1.5 -1.2 -1.2 -0.8 -1.0 -0.8 -0.2 0.0 -0.2 -0.3 -1.0 -0.7 -1.1 -0.9 -0.6 -0.8 -0.7 -0.9 1.2 0.3 -0.6 0.3
Sitting height 0.5 3.4 6.0 0.9 1.9 1.8 1.9 1.4 1.9 0.0 2.5 1.4 2.0 2.3 1.9 2.0 2.4 2.2 2.3 2.0 -2.2 0.5 1.9 0.5
Chronic bronchitis/emphysema (father) 0.3 0.3 2.2 0.9 0.0 -0.0 -0.1 -0.6 -0.4 0.0 -0.6 -0.1 -0.2 0.3 0.8 -0.0 -0.4 -0.1 -0.0 0.0 0.4 1.2 0.3 1.5
High blood pressure (mother) 0.3 0.5 2.6 1.6 -0.1 -0.3 -0.3 -1.4 -0.4 0.0 0.7 -0.4 -0.2 -0.3 -0.8 -0.3 -0.5 -0.5 -0.4 -0.2 0.8 0.8 -0.2 1.0
Body mass index (BMI) 0.2 0.8 1.6 -0.9 -1.0 -1.1 -1.1 -1.1 -0.2 0.0 -0.0 -1.0 -1.1 0.3 -1.0 -1.2 -1.3 -1.1 -1.0 -1.1 1.1 -0.2 -0.9 0.1
Impedance of leg (left) 0.4 2.0 3.7 -1.3 -1.9 -1.6 -1.6 -1.7 -0.4 0.0 -1.1 -0.5 -1.5 -1.8 -1.5 -1.6 -1.3 -1.7 -1.6 -1.8 1.8 -0.1 -1.8 -0.4
Leg predicted mass (left) 0.2 0.8 3.2 0.4 1.0 0.8 0.9 1.3 0.5 0.0 0.9 0.7 0.8 1.8 0.9 0.9 0.7 1.1 1.0 1.0 -1.1 0.2 1.0 0.5
Trunk fat mass 0.6 2.4 3.8 -1.8 -1.9 -1.9 -1.9 -1.7 -0.8 0.0 -0.8 -1.3 -1.9 -0.2 -1.8 -2.0 -1.9 -1.9 -1.8 -2.0 1.7 -0.3 -1.8 -0.0
Waist circumference 0.2 0.8 1.6 -1.0 -1.0 -1.1 -1.1 -1.1 -0.2 0.0 -0.1 -0.8 -1.1 0.5 -0.8 -1.1 -1.3 -1.1 -1.1 -1.1 1.2 0.3 -0.9 0.6
Number of incorrect matches in round 0.4 0.6 1.3 -0.9 -1.0 -0.8 -0.8 0.2 -0.9 0.0 -0.5 -0.7 -0.9 -0.2 -1.1 -0.9 -0.6 -0.9 -0.8 -1.0 0.5 -0.5 -1.2 -0.5
Past tobacco smoking 1.9 3.4 7.1 1.6 2.2 2.1 2.2 1.0 1.4 0.0 1.5 0.5 2.3 0.5 1.9 2.1 2.5 2.3 2.3 2.3 -2.7 -1.2 2.0 -1.6
Alcohol usually taken with meals 0.2 0.2 1.3 -1.0 -0.2 -0.2 -0.1 1.1 0.4 0.0 1.1 -0.9 -0.1 -0.2 -0.0 -0.0 0.3 0.1 0.2 0.1 -0.6 -0.1 -0.3 0.1
Nervous feelings 3.3 6.1 10.3 -1.8 -3.2 -2.8 -2.9 -2.2 -2.2 0.0 -1.7 -1.4 -2.8 -3.2 -2.9 -2.9 -2.7 -2.7 -2.7 -2.8 3.0 -1.1 -2.8 -1.0
Frequency of tenseness / restlessness in last 2 weeks 2.1 3.2 6.5 -1.3 -2.1 -1.9 -1.9 -1.9 -2.4 0.0 -2.5 -0.3 -1.9 -1.3 -2.0 -1.8 -1.9 -1.7 -1.9 -2.2 1.9 -1.4 -2.0 -1.3
Hearing difficulty/problems with background noise 0.8 1.2 3.7 0.2 1.2 0.9 1.0 1.9 1.2 0.0 0.8 -0.6 1.0 1.2 1.0 0.9 1.4 1.2 1.4 1.2 -1.3 -1.0 0.9 -1.0
Hair/balding pattern: Pattern 2 0.6 0.8 5.4 0.5 1.0 0.7 0.8 2.3 0.3 0.0 -0.5 -0.3 0.6 0.8 1.0 0.8 0.9 1.1 1.0 1.2 -0.7 0.3 0.9 0.4
Had menopause 1.0 1.3 7.9 0.9 0.3 0.4 0.5 1.1 1.5 0.0 2.1 0.3 0.5 0.7 -0.0 0.3 0.7 0.6 0.5 0.3 -0.0 2.8 0.4 2.8
Had other major operations 0.7 0.8 2.1 -1.4 -0.8 -1.0 -0.9 0.2 0.0 0.0 0.3 -1.3 -1.1 0.1 -0.6 -0.9 -1.0 -0.5 -0.8 -1.1 1.1 1.1 -0.8 1.4
Forced vital capacity (FVC) 0.4 1.6 2.8 0.7 1.1 1.3 1.2 1.4 1.2 0.0 1.5 1.7 1.2 0.8 1.6 1.4 1.4 1.6 1.4 1.6 -1.2 0.8 1.5 0.8
Heel bone mineral density (BMD) T-score, automated (right) 1.5 3.4 7.8 1.0 2.0 2.2 2.1 2.8 2.1 0.0 1.4 1.1 2.0 1.2 2.3 2.1 2.0 2.1 1.9 2.2 -2.2 0.7 2.0 0.9
Ever unenthusiastic/disinterested for a whole week 2.1 2.5 8.6 -0.7 -1.5 -1.5 -1.5 -2.4 -2.6 0.0 -2.9 -0.6 -1.4 -1.9 -1.3 -1.5 -1.6 -1.5 -1.6 -1.6 1.5 -0.5 -1.4 -0.6
Qualifications: None of the above 0.2 0.5 1.0 -0.6 -0.7 -0.9 -0.8 -0.9 -0.2 0.0 -0.9 -0.4 -0.8 0.0 -0.4 -0.7 -0.5 -0.7 -0.5 -1.0 0.8 -1.0 -0.8 -1.0
Financial difficulties in last 2 years 0.9 1.2 2.6 -1.1 -1.2 -1.3 -1.2 -1.2 -0.2 0.0 -0.2 -1.1 -1.2 0.1 -0.7 -1.3 -1.2 -1.4 -1.2 -1.6 1.4 1.3 -1.2 1.3
Mouth/teeth dental problems 3.4 5.2 9.4 -2.5 -2.2 -2.5 -2.6 -1.8 -3.1 0.0 -1.7 -2.6 -2.5 -2.3 -2.4 -2.4 -2.5 -2.3 -2.5 -2.2 2.5 -1.6 -2.3 -1.5
Heart attack 0.4 0.5 1.4 0.1 -0.7 -0.7 -0.8 -0.4 0.1 0.0 0.3 -0.7 -0.8 -0.8 -1.2 -0.8 -1.0 -0.8 -0.9 -0.8 1.0 0.6 -0.6 0.7
Allergy 1.3 3.0 7.6 2.2 1.8 1.9 1.7 0.8 0.0 0.0 -1.7 2.7 1.9 2.3 1.3 1.9 2.1 1.8 1.9 1.6 -1.9 -1.3 1.6 -1.5
Pain all over the body in last month 1.6 1.7 9.4 0.3 1.2 0.8 1.1 2.4 1.1 0.0 1.0 -0.1 0.9 3.1 1.8 1.0 1.3 1.3 1.5 0.7 -1.3 0.9 0.9 1.2
Diabetes (self-reported) 1.2 1.9 5.0 -2.2 -1.5 -1.5 -1.5 -1.2 -1.1 0.0 -1.9 -1.6 -1.6 -0.3 -0.7 -1.3 -1.3 -1.2 -1.2 -1.8 1.0 -1.2 -1.6 -1.1
Hayfever/allergic rhinitis (self-reported) 0.3 0.4 1.3 -1.1 -0.6 -0.4 -0.7 -0.5 0.1 0.0 -0.8 -1.1 -0.7 -0.7 -0.2 -0.6 -1.0 -0.7 -1.0 -0.4 0.5 0.3 -0.5 0.4
Medication: Ramipril 0.7 0.9 1.9 0.2 -1.4 -1.1 -1.2 -1.0 -1.2 0.0 -0.8 -0.4 -1.2 0.2 -0.8 -1.2 -1.2 -1.2 -1.1 -1.0 1.1 0.7 -0.9 1.0
Medication: Simvastatin 0.2 0.4 1.6 -1.3 -0.8 -0.6 -0.6 0.0 -0.5 0.0 -0.7 0.2 -0.6 -0.0 -0.6 -0.5 -0.6 -0.5 -0.4 -0.7 0.5 -0.9 -0.5 -0.7
Fluid intelligence score 0.2 0.3 2.1 -0.3 0.3 0.3 0.2 1.0 0.3 0.0 1.3 0.5 0.5 -1.5 -0.4 0.3 0.3 0.4 0.0 0.4 -0.0 0.7 0.3 0.4
Illnesses of siblings 0.4 0.5 1.7 1.3 0.7 0.8 0.8 0.9 0.0 0.0 -0.6 0.9 0.8 0.3 1.0 0.7 0.5 0.7 0.4 0.9 -1.0 -0.5 0.6 -0.7
Neuroticism score 2.8 5.9 12.9 -1.2 -2.7 -2.4 -2.5 -2.8 -2.6 0.0 -2.7 -1.0 -2.4 -3.6 -3.0 -2.6 -2.5 -2.6 -2.6 -2.3 2.4 -1.9 -2.6 -2.0
Weight 0.0 0.2 0.9 -0.7 -0.3 -0.5 -0.4 -0.0 0.3 0.0 0.7 -0.2 -0.4 0.9 -0.3 -0.5 -0.5 -0.3 -0.3 -0.4 0.4 0.2 -0.3 0.4
Impedance of arm (right) 0.4 1.7 3.0 -1.1 -1.6 -1.4 -1.5 -1.3 -1.0 0.0 -1.2 -1.0 -1.4 -1.6 -1.7 -1.4 -1.1 -1.5 -1.4 -1.6 1.1 -0.5 -1.7 -0.7
Arm fat percentage (right) 0.7 2.9 4.5 -1.6 -1.9 -2.0 -2.0 -2.1 -1.2 0.0 -1.2 -1.5 -2.0 -0.4 -2.0 -2.1 -2.1 -2.1 -1.9 -2.1 1.9 -0.6 -1.9 -0.4
Trunk fat-free mass 0.3 1.6 4.9 0.5 1.4 1.2 1.2 2.2 1.0 0.0 1.3 1.2 1.2 1.9 1.7 1.3 1.1 1.4 1.3 1.4 -1.1 0.5 1.4 0.7
Hip circumference 0.3 1.1 2.0 -1.4 -1.3 -1.3 -1.3 -0.9 -0.2 0.0 -0.3 -0.4 -1.3 0.5 -1.3 -1.4 -1.2 -1.1 -1.1 -1.4 1.3 0.4 -1.2 0.6
Time employed in main current job 1.1 1.3 5.1 -1.9 -0.8 -1.1 -0.9 -0.5 -0.1 0.0 -0.4 -2.2 -1.0 -1.8 -1.3 -1.3 -0.8 -1.0 -1.0 -0.8 1.2 0.8 -1.2 0.8
Alcohol intake versus 10 years previously 0.2 0.3 1.3 0.2 -0.5 -0.3 -0.5 -0.2 -0.3 0.0 -0.4 0.6 -0.4 -0.1 -1.1 -0.5 -0.5 -0.6 -0.7 -0.6 0.9 1.0 -0.4 0.8
Father’s age at death 0.5 0.6 1.5 -0.4 0.8 1.0 0.9 0.7 -0.0 0.0 -0.6 1.0 0.9 0.4 1.2 1.1 0.8 1.0 0.8 0.9 -0.9 0.5 0.6 0.4
Worrier / anxious feelings 2.1 4.0 6.5 -1.6 -2.5 -2.4 -2.4 -2.1 -1.8 0.0 -1.2 -0.8 -2.3 -2.2 -2.4 -2.3 -2.4 -2.4 -2.4 -2.3 2.3 -1.1 -2.1 -1.0
Frequency of tiredness / lethargy in last 2 weeks 0.8 1.4 2.8 0.0 -1.4 -1.4 -1.5 -1.0 -0.4 0.0 -0.1 -1.2 -1.4 -0.4 -1.5 -1.4 -1.4 -1.2 -1.3 -1.7 1.6 0.5 -1.4 0.7
Falls in the last year 1.0 1.3 2.5 -1.2 -1.2 -1.2 -1.3 -0.7 -1.2 0.0 -1.6 -0.7 -1.3 -0.3 -1.4 -1.4 -1.2 -1.2 -1.2 -1.5 1.2 -0.6 -1.6 -0.7
Hair/balding pattern: Pattern 3 0.9 1.3 5.3 0.2 -1.1 -0.9 -1.0 -1.4 -1.4 0.0 -0.7 -0.1 -0.8 -0.8 -0.8 -0.9 -1.0 -1.1 -1.0 -1.4 0.6 -2.3 -1.1 -2.3
Number of live births 0.3 0.4 2.4 -0.4 -0.6 -0.5 -0.5 -0.4 0.9 0.0 0.8 -0.3 -0.5 -0.3 -0.0 -0.5 -0.2 -0.4 -0.3 -0.4 0.8 1.4 -0.2 1.5
Forced expiratory volume in 1-second (FEV1) 0.0 0.1 0.5 0.0 -0.3 -0.1 -0.1 -0.2 -0.2 0.0 0.5 0.7 -0.0 -0.4 0.1 0.1 -0.1 0.1 -0.0 0.2 0.1 0.1 0.1 0.2
Pulse rate 1.2 2.0 6.0 -0.0 -1.6 -1.6 -1.7 -2.5 -1.9 0.0 -1.2 -0.4 -1.5 -0.8 -1.5 -1.7 -1.6 -1.9 -1.6 -1.5 1.8 -0.3 -1.2 -0.3
Happiness 2.4 2.9 10.7 -0.9 -1.6 -1.6 -1.5 -1.9 -2.7 0.0 -3.3 -0.8 -1.4 -1.0 -1.8 -1.7 -1.9 -1.7 -1.7 -1.7 1.6 -1.3 -1.4 -1.2
Noisy workplace 0.6 0.7 3.1 0.6 0.8 0.9 0.9 -0.5 1.8 0.0 0.9 0.5 0.9 0.6 0.4 0.9 0.9 0.7 0.9 1.1 -0.9 -0.4 0.9 -0.5
Qualifications: A levels/AS levels or equivalent 0.0 0.1 0.9 -0.4 0.0 0.2 0.2 0.3 -0.1 0.0 -0.1 0.2 0.2 -0.9 0.1 0.2 0.2 0.5 0.1 0.4 0.0 0.4 0.2 0.3
Serious illness, injury or assault of a close relative in last 2 years 0.6 0.7 2.8 1.7 0.6 0.7 0.7 -0.4 1.4 0.0 1.6 1.2 0.8 1.0 0.1 0.6 0.9 0.6 0.8 0.8 -0.7 0.4 0.7 0.3
Mouth/teeth dental problems: Dentures 1.8 3.1 5.6 1.0 1.8 1.9 1.9 2.1 2.4 0.0 1.8 2.0 1.8 2.3 2.2 1.8 1.9 1.7 1.9 1.7 -1.8 0.2 2.0 0.1
Asthma 0.5 1.0 7.1 -0.9 -0.5 -0.4 -0.4 1.1 0.9 0.0 1.1 -0.2 -0.7 1.0 -0.1 -0.5 -0.6 -0.3 -0.5 -0.5 0.7 2.5 0.0 2.7
Medication: Ibuprofen (e.g. Nurofen) 0.4 0.5 1.7 -0.4 0.6 0.5 0.5 -0.8 -0.3 0.0 -1.0 0.5 0.6 -1.3 0.8 0.5 0.3 0.6 0.3 0.9 -0.9 -1.0 0.5 -1.0
Medication: Cholesterol lowering 0.4 0.6 2.4 -0.4 -0.9 -0.7 -0.8 -1.2 -1.3 0.0 -1.5 -0.4 -0.9 -0.3 -0.6 -0.6 -0.8 -0.9 -0.6 -0.8 0.6 -0.2 -0.6 0.0
Depression (self-reported) 0.4 0.5 3.2 -0.3 0.4 0.1 0.2 0.9 1.1 0.0 0.7 -1.8 0.1 0.6 -0.1 0.2 0.3 0.4 0.4 0.4 -0.5 1.0 0.1 1.2
Medication: Lansoprazole 1.4 1.6 3.0 -1.7 -1.6 -1.4 -1.4 -1.0 -0.8 0.0 -0.6 -1.6 -1.6 -0.2 -1.6 -1.4 -1.1 -1.4 -1.2 -1.6 1.4 0.2 -1.6 0.5
Prospective memory result 1.3 1.6 7.8 -0.3 -1.0 -1.0 -1.0 -1.7 -2.0 0.0 -2.8 -0.4 -1.0 -0.4 -0.3 -0.8 -0.9 -1.1 -0.9 -1.1 0.6 -1.9 -1.0 -2.0
Lung cancer (father) 1.0 1.2 2.9 -1.7 -1.3 -1.1 -1.1 -0.1 -0.7 0.0 -1.0 -1.4 -1.0 -1.6 -1.2 -1.0 -1.0 -1.1 -1.1 -1.1 0.9 -0.8 -1.3 -0.9
Illnesses of mother 0.3 0.4 0.9 -0.6 0.3 0.5 0.4 0.9 0.2 0.0 -0.7 1.0 0.4 -0.1 0.8 0.4 0.5 0.6 0.4 0.7 -0.7 -0.8 0.3 -0.9
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.2 1.1 0.1 -0.1 0.1 0.0 0.2 0.4 0.0 1.1 0.9 0.1 -0.0 0.1 0.2 0.2 0.2 0.1 0.5 0.3 0.8 0.4 0.8
Pulse wave Arterial Stiffness index 0.6 0.7 3.6 -1.8 -0.0 -0.0 -0.1 0.1 1.6 0.0 1.3 -0.3 -0.2 0.8 0.3 0.0 0.1 -0.1 0.1 0.2 0.5 1.7 0.3 1.9
Impedance of arm (left) 0.5 2.3 4.1 -1.2 -1.8 -1.6 -1.7 -1.9 -1.3 0.0 -1.6 -1.0 -1.6 -1.5 -2.0 -1.6 -1.4 -1.8 -1.6 -1.9 1.2 -0.7 -1.9 -0.9
Arm fat mass (right) 0.4 1.5 2.6 -1.6 -1.4 -1.5 -1.5 -1.4 -0.7 0.0 -0.7 -0.9 -1.5 0.1 -1.4 -1.6 -1.6 -1.5 -1.4 -1.5 1.5 -0.3 -1.3 -0.1
Trunk predicted mass 0.3 1.6 4.9 0.5 1.4 1.2 1.2 2.2 0.8 0.0 1.2 1.2 1.2 1.9 1.7 1.3 1.1 1.4 1.3 1.4 -1.1 0.6 1.4 0.8
Standing height 0.2 1.8 5.9 0.2 1.3 1.2 1.3 2.4 1.1 0.0 1.5 1.4 1.4 1.6 1.4 1.4 1.6 1.6 1.4 1.3 -1.5 0.6 1.2 0.6
Length of working week for main job 0.2 0.2 1.3 -0.4 0.2 0.1 0.1 0.3 0.7 0.0 0.9 0.4 0.1 0.5 0.1 0.1 0.4 0.1 0.2 0.2 -0.3 -0.9 0.2 -1.2
Exposure to tobacco smoke at home 0.9 1.1 6.2 -1.8 -0.4 -0.5 -0.5 -1.6 -0.9 0.0 -1.1 -0.1 -0.3 -0.5 -0.3 -0.4 -0.1 -0.6 -0.2 -0.4 -0.1 -2.4 -0.8 -2.5
Breastfed as a baby 0.1 0.2 1.2 -1.1 -0.4 -0.2 -0.2 0.2 -0.5 0.0 0.0 0.0 -0.3 -0.0 -0.7 -0.3 0.1 0.0 0.0 -0.4 0.2 0.6 -0.2 0.7
Tense / ‘highly strung’ 8.8 14.6 20.3 -3.0 -4.5 -4.1 -4.2 -3.8 -3.7 0.0 -3.3 -2.0 -4.0 -4.2 -4.5 -4.4 -4.1 -4.4 -4.2 -4.4 3.9 -3.1 -4.2 -3.3
Seen doctor (GP) for nerves, anxiety, tension or depression 3.9 6.0 10.3 -3.2 -2.9 -3.0 -2.9 -1.2 -2.5 0.0 -2.5 -2.3 -3.0 -2.0 -2.6 -2.9 -2.5 -2.7 -2.5 -2.9 2.7 -0.4 -2.8 -0.2
Hair/balding pattern: Pattern 4 0.1 0.3 1.4 0.2 0.2 0.3 0.3 -1.2 -0.4 0.0 -0.8 1.1 0.4 -0.4 0.5 0.3 0.1 0.2 0.3 0.4 -0.4 -0.8 0.6 -0.8
Birth weight of first child 0.3 0.6 1.5 -1.2 0.7 0.8 0.8 0.8 -0.3 0.0 -1.2 0.6 0.7 -0.0 0.8 0.7 1.0 0.9 0.9 0.8 -0.9 0.3 0.7 0.1
Peak expiratory flow (PEF) 0.1 0.3 1.2 0.0 -0.4 -0.2 -0.2 -0.7 -0.6 0.0 -0.1 1.0 -0.2 -0.7 -0.2 -0.2 -0.5 -0.1 -0.4 0.2 0.4 1.0 0.0 1.1
Pulse wave reflection index 1.4 1.7 4.3 -0.4 1.0 1.3 1.3 1.3 2.1 0.0 1.8 1.3 1.2 1.0 1.3 1.3 1.4 1.4 1.4 1.2 -0.9 1.5 1.3 1.4
Ever highly irritable/argumentative for 2 days 0.9 1.1 3.8 0.7 0.4 0.6 0.6 0.5 1.9 0.0 1.0 1.2 0.5 1.6 1.3 0.6 0.6 0.5 0.8 0.6 -0.4 1.8 0.6 2.0
Loud music exposure frequency 2.3 2.5 4.2 2.1 1.6 1.7 1.7 0.4 2.1 0.0 1.9 1.7 1.8 1.0 1.6 1.5 1.8 1.7 1.7 1.7 -1.3 1.6 1.3 1.4
Qualifications: O levels/GCSEs or equivalent 0.6 0.9 3.4 1.0 0.9 1.1 1.1 1.8 0.4 0.0 0.1 0.3 1.2 0.2 0.9 1.1 1.1 1.3 1.0 1.1 -1.3 -0.3 1.1 -0.4
Mouth/teeth dental problems: Bleeding gums 0.4 0.5 2.9 1.0 0.2 0.3 0.3 0.1 1.7 0.0 1.2 1.2 0.4 0.2 0.4 0.3 0.4 0.3 0.3 0.3 -0.1 1.2 0.3 1.1
Blood clot in the leg (DVT) 0.6 0.8 2.4 1.1 1.1 0.7 0.8 1.6 0.2 0.0 1.1 -1.5 0.7 -0.1 0.9 0.8 0.8 1.0 1.0 0.7 -1.1 -0.4 0.5 -0.1
Medication: Paracetamol 0.2 0.3 2.2 -0.2 -0.3 0.1 -0.1 -0.0 -0.0 0.0 -1.1 0.4 0.1 -0.6 0.1 -0.1 -0.3 -0.2 -0.3 -0.1 -0.3 -1.5 -0.2 -1.5
Headache pain in last month 0.2 0.3 2.5 -0.4 -0.2 -0.1 -0.1 -1.6 -1.0 0.0 -0.8 -0.1 -0.1 -0.6 -0.5 -0.3 -0.1 -0.3 -0.1 -0.1 -0.0 -0.7 -0.1 -0.7
Medication for cholesterol, blood pressure or diabetes 0.4 0.7 3.3 -0.3 0.8 0.5 0.7 1.7 1.4 0.0 1.8 -0.5 0.7 -0.1 0.6 0.5 0.7 1.0 0.6 0.8 -0.9 -0.7 0.2 -0.7
Glaucoma (self-reported) 0.5 0.5 4.0 -0.5 -0.2 -0.0 -0.0 0.5 -0.5 0.0 -1.4 0.1 0.1 -0.7 -0.1 -0.2 -0.1 0.1 -0.2 -0.1 -0.5 -1.9 -0.3 -2.0
Gout (self-reported) 0.5 0.6 3.0 1.5 -0.1 -0.0 -0.2 -1.7 -1.5 0.0 -1.1 1.7 -0.2 0.6 -0.3 -0.2 -0.2 -0.5 -0.0 -0.2 0.5 0.2 0.0 0.1
Hypothyroidism/myxoedema (self-reported) 0.2 0.3 1.0 -0.8 -0.8 -0.4 -0.6 -0.5 -1.0 0.0 -0.9 -0.1 -0.6 -0.3 -0.6 -0.4 -0.5 -0.4 -0.5 -0.7 0.6 -0.3 -0.2 -0.3
Medication: Amlodipine 0.6 0.8 3.6 1.8 0.6 0.9 0.7 -0.5 -0.2 0.0 -0.7 1.9 0.9 1.0 0.5 0.8 0.2 0.4 0.4 0.7 -0.2 1.2 1.1 1.1
Medication: Ventolin 100micrograms inhaler 0.2 0.3 0.7 -0.4 -0.5 -0.6 -0.5 -0.1 0.1 0.0 0.3 -0.6 -0.6 -0.5 -0.9 -0.6 -0.6 -0.6 -0.8 -0.7 0.6 0.4 -0.6 0.5
Birth weight 0.2 0.4 2.8 -1.1 0.1 -0.2 -0.2 1.7 -0.8 0.0 -0.1 -0.3 -0.1 0.1 0.9 -0.0 -0.4 0.2 -0.0 -0.2 0.2 -1.0 0.1 -0.7
Chronic bronchitis/emphysema (mother) 0.2 0.2 1.0 -0.5 -0.2 -0.2 -0.2 0.4 0.6 0.0 1.0 -1.0 -0.4 0.1 -0.4 -0.3 -0.2 -0.2 -0.1 -0.4 0.4 0.8 -0.2 1.0
High blood pressure (siblings) 0.2 0.2 1.0 -0.2 -0.3 -0.5 -0.4 -1.0 -0.4 0.0 0.3 -0.6 -0.4 0.3 -0.8 -0.4 -0.1 -0.3 -0.0 -0.5 0.5 0.6 -0.2 0.7
Forced vital capacity (FVC), Best measure 0.6 2.1 4.4 0.8 1.2 1.4 1.3 1.6 1.8 0.0 2.1 2.0 1.3 1.2 1.6 1.5 1.6 1.6 1.5 1.6 -0.9 1.4 1.6 1.3
Body fat percentage 0.9 3.7 6.0 -1.8 -2.4 -2.3 -2.3 -2.4 -1.0 0.0 -1.0 -1.5 -2.3 -0.6 -2.3 -2.4 -2.4 -2.4 -2.2 -2.4 2.2 -0.4 -2.2 -0.2
Leg fat percentage (right) 0.5 1.6 3.0 -1.0 -1.7 -1.6 -1.6 -1.5 -0.2 0.0 -0.6 -0.7 -1.6 0.4 -1.4 -1.6 -1.6 -1.6 -1.4 -1.7 1.7 0.3 -1.4 0.5
Arm fat-free mass (right) 0.1 0.6 2.4 0.4 0.9 0.7 0.7 1.1 0.7 0.0 1.1 0.5 0.7 1.5 1.0 0.7 0.5 0.9 0.7 0.8 -0.8 0.4 0.9 0.6
Exposure to tobacco smoke outside home 2.0 2.6 4.8 0.8 1.9 2.0 2.1 0.8 2.1 0.0 1.0 1.4 2.2 0.8 1.6 2.0 1.9 1.9 1.8 1.9 -2.1 0.8 1.7 0.7
Comparative body size at age 10 0.1 0.4 1.5 -0.4 -0.3 -0.6 -0.7 -0.2 -0.4 0.0 1.0 -0.0 -0.8 0.2 -0.6 -0.7 -0.6 -0.7 -0.4 -0.4 1.2 0.8 -0.3 0.9
Number of full brothers 0.2 0.3 1.6 -0.4 -0.2 -0.4 -0.4 -0.6 0.0 0.0 0.4 -0.6 -0.1 -0.3 -0.8 -0.4 -0.1 -0.6 -0.5 -0.5 0.3 -1.0 -0.5 -1.2
Worry too long after embarrassment 0.2 0.4 1.7 -0.2 -0.5 -0.3 -0.3 0.0 -0.9 0.0 -1.0 -0.2 -0.2 -1.3 -1.1 -0.6 -0.1 -0.1 -0.2 -0.3 0.1 -0.9 -0.5 -1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.5 2.0 4.9 -1.3 -1.5 -1.6 -1.6 0.2 -2.2 0.0 -2.2 -0.7 -1.6 -0.8 -1.6 -1.6 -1.4 -1.4 -1.6 -1.7 1.5 -0.4 -1.5 -0.4
Wheeze or whistling in the chest in last year 0.4 0.8 1.6 -0.1 -1.1 -0.8 -0.9 -0.5 0.3 0.0 -0.2 0.1 -1.0 0.5 -0.8 -0.9 -1.2 -1.1 -1.2 -1.1 1.3 1.2 -0.7 1.1
Number of children fathered 0.1 0.1 1.3 -0.6 -0.1 0.0 -0.0 0.7 0.5 0.0 1.2 -0.5 0.0 -0.5 0.2 -0.1 0.2 -0.1 -0.0 0.3 -0.2 0.2 -0.0 0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.2 0.3 1.0 0.9 0.4 0.6 0.6 0.8 0.1 0.0 0.1 0.8 0.4 0.1 1.0 0.5 0.5 0.4 0.5 0.7 -0.5 0.2 0.4 0.2
Age at first live birth 0.3 0.5 1.8 0.6 0.7 0.8 0.8 0.7 0.1 0.0 -0.0 0.9 0.7 0.2 0.6 0.7 0.5 0.9 0.5 1.0 -0.5 1.3 0.7 1.3
Pulse wave peak to peak time 0.7 0.8 3.6 1.7 -0.1 -0.1 -0.0 -0.2 -1.8 0.0 -1.4 0.2 0.1 -1.0 -0.5 -0.1 -0.2 -0.0 -0.3 -0.3 -0.4 -1.7 -0.5 -1.9
Health satisfaction 2.9 3.8 7.2 -1.6 -2.6 -2.2 -2.2 -1.4 -0.8 0.0 -0.8 -0.2 -2.1 -1.6 -2.5 -2.5 -2.7 -2.4 -2.6 -2.4 2.6 -0.0 -2.3 -0.0
Shortness of breath walking on level ground 0.6 0.7 1.6 -1.1 -0.8 -0.9 -0.8 -1.3 -0.8 0.0 -0.7 -0.9 -0.8 -0.5 -0.9 -0.9 -0.9 -0.9 -0.8 -1.0 0.6 -0.7 -1.0 -0.5
Qualifications: College or University degree 0.5 1.7 3.7 0.8 1.7 1.4 1.6 1.0 0.5 0.0 1.3 0.4 1.6 0.4 1.6 1.6 1.5 1.7 1.7 1.9 -1.8 -0.2 1.5 -0.1
Eye problems/disorders: None of the above 2.7 3.1 4.9 1.9 2.2 2.1 2.1 0.6 1.5 0.0 2.0 1.0 2.0 1.6 2.1 2.1 1.9 1.8 2.0 2.2 -1.9 0.6 2.0 0.7
Mouth/teeth dental problems: Loose teeth 0.8 0.9 4.3 0.1 -0.7 -0.6 -0.5 -1.8 0.6 0.0 0.8 0.1 -0.5 1.4 -0.7 -0.7 -0.4 -0.5 -0.3 -0.9 0.9 2.0 -0.5 2.1
Emphysema/chronic bronchitis 0.6 0.6 1.6 0.3 -0.9 -1.0 -1.0 -0.4 0.1 0.0 -0.4 -1.1 -0.9 -1.2 -0.8 -0.9 -1.1 -0.9 -1.0 -0.8 0.9 -0.1 -0.8 0.1
Medication for pain relief, constipation, heartburn 1.0 1.7 5.2 1.7 1.0 0.9 1.0 1.6 0.9 0.0 2.3 1.2 0.9 2.0 1.1 0.9 1.3 1.1 1.3 0.8 -0.5 2.0 1.0 1.8
Neck or shoulder pain in last month 0.2 0.2 0.9 1.0 0.1 0.1 0.2 0.3 0.1 0.0 -0.9 0.7 0.1 0.7 -0.4 0.1 -0.3 0.2 -0.0 -0.0 -0.3 0.8 0.5 0.9
Medication: Blood pressure 0.6 1.1 4.8 0.3 -0.9 -0.6 -0.8 -1.8 -1.9 0.0 -2.2 0.7 -0.7 -0.6 -1.3 -0.7 -0.9 -1.2 -0.8 -0.9 1.2 -0.0 -0.4 -0.2
Angina (self-reported) 0.5 0.7 1.6 -0.4 -1.1 -0.8 -0.9 -1.0 0.1 0.0 -0.8 0.0 -1.0 -0.0 -1.3 -0.8 -0.9 -1.2 -0.9 -1.0 0.9 0.8 -0.8 0.9
Migraine (self-reported) 0.2 0.3 1.1 -0.3 -0.7 -0.4 -0.5 -0.5 -0.6 0.0 -0.8 -0.3 -0.6 0.4 -1.1 -0.6 -0.4 -0.5 -0.5 -0.7 0.5 -0.0 -0.5 -0.2
Medication: Ibuprofen 0.3 0.4 2.6 -0.7 -0.1 -0.2 -0.1 -1.2 -0.6 0.0 -1.6 -0.1 -0.1 -1.2 0.2 -0.1 -0.2 -0.1 -0.2 0.1 -0.2 -0.8 -0.2 -0.6
Medication: Allopurinol 0.4 0.6 2.4 0.9 0.0 -0.0 -0.0 -1.5 -1.5 0.0 -1.3 0.9 -0.1 0.1 -0.1 0.1 -0.0 -0.3 0.2 -0.0 -0.1 -1.3 -0.0 -1.3
Medication: Omeprazole 0.8 1.0 5.8 -0.9 -0.8 -0.5 -0.7 -0.3 -0.3 0.0 -0.7 0.4 -0.7 0.2 -0.8 -0.7 -0.6 -0.5 -0.6 -1.1 1.4 2.4 -0.5 2.4
Medication: Seretide 50 evohaler 0.5 0.6 4.6 0.1 -0.3 -0.2 -0.2 0.7 0.7 0.0 0.4 0.6 -0.3 -0.2 -1.1 -0.4 -0.1 -0.2 -0.4 -0.3 0.8 2.1 -0.4 1.8
Mean time to correctly identify matches 0.1 0.3 1.6 -0.0 0.0 0.1 0.1 1.1 0.4 0.0 0.4 0.6 -0.1 0.6 -0.1 0.1 0.2 -0.0 0.1 0.1 0.3 1.3 0.2 1.3
Heart disease (mother) 1.6 1.9 3.3 -0.8 -1.7 -1.8 -1.6 -1.4 -0.6 0.0 -0.1 -1.8 -1.4 -1.2 -1.6 -1.7 -1.7 -1.5 -1.6 -1.8 1.4 -1.0 -1.6 -0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.2 0.7 0.5 0.6 0.6 1.0 0.9 0.0 1.0 1.1 0.7 0.9 0.5 0.5 0.8 0.9 0.8 0.4 -0.1 0.9 0.4 0.7
Whole body fat mass 0.3 1.3 2.2 -1.3 -1.4 -1.4 -1.4 -1.2 -0.5 0.0 -0.5 -0.8 -1.4 0.4 -1.3 -1.5 -1.5 -1.4 -1.3 -1.5 1.3 -0.1 -1.2 0.1
Leg fat mass (right) 0.2 0.8 1.5 -1.0 -1.1 -1.2 -1.1 -0.8 0.0 0.0 -0.0 -0.4 -1.1 0.7 -0.8 -1.2 -1.2 -1.1 -0.9 -1.2 1.2 0.2 -0.9 0.3
Arm predicted mass (right) 0.1 0.6 2.0 0.2 0.8 0.7 0.7 1.1 0.8 0.0 1.2 0.7 0.7 1.4 1.0 0.7 0.6 0.9 0.7 0.8 -0.7 0.3 0.9 0.4
Pulse rate, automated reading 0.3 1.0 2.3 -0.1 -0.8 -1.1 -1.1 -1.5 -1.1 0.0 -1.0 -0.7 -1.1 0.5 -1.4 -1.1 -1.0 -1.3 -1.0 -1.2 1.2 -0.6 -0.7 -0.6
Alcohol intake frequency. 0.7 1.6 2.3 1.1 1.4 1.5 1.5 0.6 1.3 0.0 1.0 0.8 1.4 0.7 1.1 1.5 1.5 1.4 1.4 1.5 -1.0 1.5 1.4 1.4
Comparative height size at age 10 0.0 0.2 2.7 -0.4 -0.1 -0.3 -0.3 0.2 0.2 0.0 1.6 -0.6 -0.3 0.9 0.2 0.0 0.2 -0.0 0.3 0.1 0.1 -0.2 -0.0 0.0
Number of full sisters 0.2 0.2 2.5 -1.6 0.0 0.0 -0.0 -0.6 -0.6 0.0 -0.9 0.5 0.1 -0.3 -0.0 -0.3 -0.1 -0.0 0.0 -0.1 0.6 -0.3 -0.0 -0.5
Suffer from ‘nerves’ 5.8 9.2 13.7 -2.2 -3.7 -3.5 -3.6 -2.6 -2.5 0.0 -1.9 -1.8 -3.5 -3.7 -3.6 -3.6 -3.3 -3.5 -3.6 -3.3 3.7 -1.6 -3.4 -1.6
Overall health rating 0.8 1.7 3.4 -0.0 -1.5 -1.4 -1.4 -0.3 -0.6 0.0 -1.0 -0.6 -1.4 0.6 -1.7 -1.5 -1.7 -1.5 -1.6 -1.8 1.8 1.3 -1.2 1.5
Chest pain or discomfort 1.3 1.8 5.3 2.0 0.9 1.2 1.1 0.8 1.7 0.0 1.9 1.9 1.0 1.3 0.6 1.2 1.0 1.1 1.0 1.1 -0.5 2.3 1.0 2.3
Had major operations 0.2 0.2 0.9 0.6 -0.0 0.1 0.0 -0.8 1.0 0.0 0.5 0.0 -0.1 0.4 -0.2 0.2 -0.1 -0.3 0.0 0.3 0.3 0.9 0.2 0.9
Age at last live birth 1.1 1.6 3.1 1.3 1.3 1.4 1.4 -0.3 -0.7 0.0 -1.2 1.3 1.3 1.8 1.6 1.4 1.2 1.4 1.4 1.3 -1.2 1.2 1.4 1.3
Family relationship satisfaction 3.7 4.6 8.0 -1.4 -2.4 -2.3 -2.3 -2.4 -2.8 0.0 -2.0 -1.6 -2.2 -2.0 -2.4 -2.4 -2.6 -2.4 -2.4 -2.4 2.4 -1.3 -2.3 -1.1
Leg pain on walking 0.0 0.0 0.3 0.2 -0.1 -0.0 -0.0 -0.2 0.4 0.0 0.1 0.5 -0.1 0.3 -0.6 0.0 -0.1 -0.0 0.0 0.1 0.1 0.1 0.1 0.0
Qualifications: NVQ or HND or HNC or equivalent 1.0 1.2 2.4 1.4 1.2 1.4 1.3 0.6 0.8 0.0 0.2 1.5 1.4 1.1 1.3 1.1 1.1 1.3 1.1 1.1 -1.0 0.4 1.2 0.2
Commuting to job workplace: Car/motor vehicle 0.1 0.1 0.5 0.6 0.2 0.2 0.2 0.4 -0.2 0.0 -0.6 -0.4 0.2 0.3 0.7 0.4 -0.0 0.2 0.1 0.2 -0.4 0.2 0.2 0.4
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.3 -1.2 -0.6 -0.6 -0.6 -0.4 -1.0 0.0 -0.9 -1.2 -0.7 -1.5 -0.6 -0.7 -0.6 -0.5 -0.6 -0.3 0.5 -0.9 -0.7 -0.9
Medication: Aspirin 0.6 0.7 3.7 -1.2 -0.7 -0.5 -0.6 -1.0 -0.6 0.0 -1.2 -0.1 -0.7 -0.9 -0.3 -0.5 -0.7 -0.6 -0.5 -0.5 0.2 -1.9 -0.5 -1.8
Supplements: Vitamin C 0.4 0.5 3.3 0.0 0.3 0.5 0.4 -0.2 0.3 0.0 0.5 1.0 0.7 -1.1 0.4 0.6 0.5 0.4 0.2 0.4 -0.5 -1.5 0.2 -1.8
Knee pain experienced in last month 0.1 0.2 0.9 0.7 -0.1 -0.0 -0.0 0.4 -0.2 0.0 -0.9 0.8 -0.1 0.9 -0.2 -0.1 -0.2 0.1 -0.1 -0.4 0.1 0.4 -0.0 0.4
Hypertension (Self-reported) 0.5 1.3 5.9 2.4 0.5 0.6 0.6 0.3 0.1 0.0 1.0 1.5 0.6 1.8 -0.0 0.7 0.7 0.5 0.7 0.5 0.1 2.4 1.0 2.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.4 0.5 3.9 -2.0 -0.8 -0.6 -0.7 0.3 0.3 0.0 -0.1 -0.2 -0.7 0.6 -0.3 -0.7 -0.3 -0.7 -0.4 -1.0 0.9 0.1 -0.6 0.2
Illnesses of father: Heart disease 0.2 0.2 1.6 0.5 -0.5 -0.1 -0.2 -0.7 -0.2 0.0 -0.1 1.2 -0.2 -0.5 -1.0 -0.3 -0.3 -0.3 -0.3 -0.3 0.3 0.5 -0.2 0.3
Illnesses of siblings: Diabetes 0.3 0.3 3.8 -0.9 -0.3 -0.3 -0.2 1.0 0.2 0.0 0.6 -2.0 -0.3 -0.1 -0.1 -0.2 -0.1 0.0 -0.1 -0.3 -0.2 -0.2 -0.4 -0.0
Smoking status: Previous 0.7 1.1 2.3 -0.8 -1.1 -1.0 -1.1 -0.2 -0.9 0.0 -0.8 0.2 -1.2 0.7 -0.8 -0.9 -1.3 -1.3 -1.2 -1.2 1.5 1.1 -0.8 1.5
Forced expiratory volume in 1-second (FEV1), predicted 0.1 0.3 1.3 0.3 0.4 0.4 0.3 -0.2 1.0 0.0 0.9 0.3 0.5 1.1 0.5 0.5 0.4 0.4 0.4 0.3 -0.5 0.1 0.3 0.0
Whole body fat-free mass 0.2 1.2 3.2 0.4 1.2 1.1 1.1 1.8 0.8 0.0 1.2 1.0 1.1 1.8 1.4 1.1 1.0 1.3 1.1 1.2 -1.1 0.4 1.2 0.6
Leg fat-free mass (right) 0.2 0.8 2.1 0.1 1.1 0.9 0.9 1.3 0.5 0.0 0.9 0.6 0.9 1.4 0.9 0.9 0.8 1.2 1.0 1.1 -1.2 -0.1 1.1 0.1
Arm fat percentage (left) 0.8 3.3 5.6 -1.7 -2.0 -2.1 -2.1 -2.4 -1.2 0.0 -1.3 -1.7 -2.1 -0.4 -2.2 -2.2 -2.3 -2.2 -2.1 -2.2 1.9 -0.7 -2.0 -0.4
Average weekly red wine intake 1.3 1.9 3.6 0.0 1.6 1.4 1.6 1.7 1.1 0.0 1.6 -0.1 1.3 0.6 1.5 1.6 1.4 1.6 1.6 1.6 -1.9 1.0 1.6 1.2
Handedness (chirality/laterality): Left-handed 1.2 1.5 6.0 2.4 1.0 1.2 1.1 1.1 0.7 0.0 0.8 1.5 1.1 1.5 1.0 1.2 1.1 1.2 1.2 0.8 -0.7 1.4 1.2 1.5
Mood swings 0.2 0.4 0.8 -0.6 -0.9 -0.7 -0.7 -0.5 0.3 0.0 -0.2 0.5 -0.8 -0.7 -0.6 -0.7 -0.8 -0.7 -0.8 -0.8 0.8 -0.3 -0.6 -0.5
Loneliness, isolation 3.9 5.4 8.3 -2.4 -2.7 -2.7 -2.7 -1.8 -2.4 0.0 -1.8 -1.7 -2.6 -2.4 -2.5 -2.7 -2.4 -2.7 -2.8 -2.8 2.9 -0.1 -2.8 -0.3
Long-standing illness, disability or infirmity 1.9 2.9 7.6 -1.5 -2.0 -1.9 -2.0 -1.4 -1.3 0.0 -1.4 -1.3 -2.0 -0.9 -2.8 -2.0 -2.0 -1.9 -2.1 -2.2 2.0 0.5 -1.6 0.5
Ever had bowel cancer screening 0.1 0.2 1.1 -0.4 0.1 0.1 -0.1 0.9 0.3 0.0 1.1 -0.3 0.0 -0.1 -0.4 -0.4 -0.1 -0.1 -0.2 -0.2 0.3 -0.3 -0.4 -0.5
Diabetes diagnosed by doctor 1.1 1.7 5.1 -2.3 -1.4 -1.4 -1.4 -0.9 -1.1 0.0 -1.9 -1.2 -1.5 -0.4 -0.8 -1.2 -1.2 -1.1 -1.1 -1.6 0.9 -1.5 -1.5 -1.4
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.9 4.3 0.8 0.7 0.8 0.8 0.6 0.3 0.0 0.5 1.0 0.6 0.9 1.4 0.7 0.5 0.8 0.7 0.9 -0.4 1.8 1.0 2.1
Friendships satisfaction 3.3 4.0 7.6 -1.4 -2.4 -2.2 -2.3 -2.8 -2.7 0.0 -2.1 -1.2 -2.1 -0.9 -2.2 -2.3 -2.4 -2.2 -2.2 -2.3 2.5 -0.6 -1.9 -0.4
Qualifications: nursing, teaching 0.1 0.1 0.6 0.2 -0.1 -0.3 -0.2 0.6 -0.2 0.0 0.8 -0.8 -0.3 -0.5 -0.2 -0.3 -0.2 -0.0 -0.2 0.1 -0.2 -0.2 -0.3 -0.1
Commuting to job workplace: Walk 1.4 1.5 4.5 2.1 0.9 1.3 1.1 -0.4 1.1 0.0 1.1 1.8 1.2 1.0 0.9 1.3 1.1 1.2 1.0 1.4 -0.9 1.6 1.3 1.6
Eye problems/disorders: Cataract 0.7 0.8 2.1 -0.8 -0.9 -0.9 -0.8 -0.5 -0.8 0.0 -1.4 -0.6 -0.7 -1.2 -0.4 -0.9 -1.2 -0.9 -1.0 -1.0 0.9 -0.8 -1.0 -0.9
Mouth/teeth dental problems: Mouth ulcers 0.4 0.6 2.6 1.6 0.6 0.7 0.7 0.5 -0.3 0.0 -1.1 0.4 0.7 0.5 0.3 0.6 0.5 0.7 0.6 0.5 -0.8 1.2 0.5 1.3
Medication for cholesterol 0.2 0.3 1.6 -1.1 0.2 0.2 0.2 0.8 -0.2 0.0 -0.2 -0.5 0.2 -1.3 0.6 0.2 0.2 0.3 0.1 0.4 -0.5 -1.1 -0.0 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.1 0.1 0.7 -0.8 -0.2 -0.2 -0.2 -0.4 -0.2 0.0 -0.5 0.3 -0.3 -0.4 -0.6 -0.1 -0.3 -0.3 -0.3 -0.1 0.4 -0.4 -0.0 -0.4
Back pain experienced in last month 2.2 3.1 5.6 -1.3 -2.0 -1.8 -1.9 -2.2 -1.3 0.0 -2.2 -0.8 -2.0 -1.3 -2.4 -2.0 -2.4 -2.0 -2.2 -2.0 2.3 0.1 -1.5 0.1
Mineral and other dietary supplements 0.2 0.3 1.0 0.2 0.5 0.6 0.6 0.2 1.0 0.0 0.5 0.3 0.6 0.9 0.1 0.6 0.8 0.5 0.7 0.6 -0.7 0.2 0.4 0.1
Breast cancer (self-reported) 0.5 0.5 2.3 -0.4 -0.6 -0.8 -0.8 -0.6 0.0 0.0 0.1 -1.5 -0.8 -0.3 -1.0 -0.8 -0.9 -0.9 -0.9 -0.8 0.6 -0.4 -1.0 -0.3
Asthma (self-reported) 0.6 1.1 7.5 -0.9 -0.6 -0.5 -0.5 0.9 1.0 0.0 1.0 0.1 -0.8 1.2 -0.2 -0.6 -0.7 -0.4 -0.6 -0.6 1.0 2.6 -0.1 2.7
Osteoporosis (self-reported) 0.4 0.5 3.7 1.5 0.2 0.2 0.4 0.9 0.7 0.0 -0.3 0.3 0.5 1.9 0.5 0.3 0.5 0.4 0.5 -0.1 -0.6 0.5 0.4 0.6
Osteoarthritis (self-reported) 0.5 0.6 2.4 0.5 -0.8 -0.8 -0.8 0.6 0.5 0.0 0.2 -0.5 -1.0 0.4 -0.4 -0.6 -0.9 -0.8 -0.7 -0.8 1.1 1.3 -0.6 1.5
Medication: Aspirin 0.9 1.1 4.7 -1.4 -0.9 -0.8 -0.9 -1.2 -0.7 0.0 -1.1 -0.4 -1.0 -1.0 -0.4 -0.8 -1.0 -0.9 -0.8 -0.9 0.4 -2.2 -0.8 -2.0
Medication: Gliclazide 0.6 0.7 2.3 1.0 0.7 0.7 0.8 1.2 -0.2 0.0 -1.5 1.2 0.7 0.8 1.1 0.9 0.5 0.8 0.6 0.6 -0.8 -0.3 0.6 -0.4
Illnesses of father: None of the above (group 1) 0.4 0.5 3.4 -1.8 0.0 -0.2 -0.2 0.7 0.3 0.0 -0.2 -1.3 -0.0 -0.2 0.3 0.0 0.3 -0.1 0.2 -0.2 -0.1 -1.4 -0.5 -1.5
Smoking status: Current 0.5 0.8 1.8 -1.3 -0.7 -1.0 -0.9 -1.1 -0.1 0.0 -1.0 -1.1 -0.9 -0.4 -0.7 -1.1 -0.9 -0.9 -1.0 -1.0 0.9 0.3 -1.0 0.2
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 2.0 -1.2 -0.8 -1.0 -1.0 0.5 0.6 0.0 1.4 -1.4 -1.0 -0.2 -0.9 -0.8 -0.4 -0.5 -0.5 -0.6 1.0 0.8 -0.8 1.0
Whole body water mass 0.2 1.1 3.1 0.3 1.2 1.0 1.0 1.7 0.6 0.0 1.1 0.9 1.0 1.8 1.3 1.0 0.9 1.2 1.0 1.2 -1.1 0.3 1.1 0.5
Leg predicted mass (right) 0.2 0.8 2.1 0.1 1.1 0.9 0.9 1.3 0.4 0.0 0.8 0.7 0.9 1.5 0.9 0.9 0.8 1.2 1.0 1.1 -1.2 -0.1 1.0 0.1
Arm fat mass (left) 0.3 1.2 2.1 -1.3 -1.2 -1.3 -1.3 -1.2 -0.5 0.0 -0.6 -0.9 -1.3 0.4 -1.2 -1.4 -1.4 -1.4 -1.3 -1.4 1.2 -0.4 -1.2 -0.2
Number of self-reported non-cancer illnesses 1.2 2.1 4.3 -1.4 -1.8 -1.8 -1.8 -0.8 -0.2 0.0 -0.3 -1.4 -1.9 -0.6 -1.2 -1.8 -1.9 -1.7 -1.7 -1.8 2.1 1.3 -1.2 1.4
Average weekly champagne plus white wine intake 0.8 1.1 3.2 1.8 1.1 1.1 1.2 1.2 0.2 0.0 1.1 1.4 1.1 0.9 1.1 1.2 1.1 1.1 1.3 1.2 -1.1 0.2 0.9 0.3
Miserableness 0.2 0.3 1.6 -0.6 -0.6 -0.3 -0.4 -0.1 -0.9 0.0 -1.1 0.0 -0.5 -1.3 -0.6 -0.5 -0.5 -0.4 -0.5 -0.4 0.5 0.0 -0.6 -0.1
Guilty feelings 0.9 1.3 5.4 2.3 1.1 1.3 1.4 0.1 0.5 0.0 0.5 0.8 1.3 0.8 0.4 1.4 1.4 1.1 1.3 1.5 -1.4 0.2 1.4 0.2
Wears glasses or contact lenses 1.6 1.8 3.3 -1.4 -1.5 -1.4 -1.4 -1.7 -1.5 0.0 -1.6 -0.6 -1.4 -1.2 -1.1 -1.6 -1.4 -1.6 -1.3 -1.4 1.8 1.1 -1.3 1.2
Ever taken oral contraceptive pill 0.6 0.7 1.4 1.0 1.0 1.0 0.9 -0.8 0.7 0.0 0.0 0.8 1.1 -0.3 0.4 0.8 0.9 0.8 1.0 0.9 -0.9 -1.0 0.6 -1.2
Hearing aid user 2.6 3.0 5.4 -0.3 -1.9 -1.8 -1.9 -2.3 -1.6 0.0 -1.4 -0.9 -1.9 -2.1 -1.8 -1.9 -2.1 -2.2 -2.1 -1.8 2.0 -1.1 -1.7 -1.1
Mother’s age at death 1.4 1.8 3.3 -0.3 1.5 1.6 1.5 1.4 1.0 0.0 1.6 0.4 1.4 0.8 1.4 1.6 1.8 1.6 1.6 1.8 -1.5 0.9 1.3 1.0
Financial situation satisfaction 2.9 3.6 6.7 -2.2 -2.3 -2.1 -2.2 -1.6 -2.1 0.0 -2.6 -1.0 -2.2 -0.5 -1.8 -2.0 -2.1 -2.3 -2.0 -2.2 2.2 -1.0 -2.0 -0.7
Tinnitus: Yes, now most or all of the time 0.8 1.0 1.9 0.5 1.0 0.9 0.9 1.1 1.3 0.0 1.3 0.7 0.9 1.4 1.3 1.1 1.2 0.8 1.2 0.9 -0.9 -0.7 1.0 -0.9
Commuting to job workplace: Public transport 0.7 0.9 6.9 0.4 0.8 0.7 0.8 0.6 1.3 0.0 2.6 0.8 0.8 0.9 0.9 0.8 0.9 0.7 0.8 0.7 -0.5 0.6 0.7 0.6
Eye problems/disorders: Glaucoma 0.3 0.4 2.7 -0.2 -0.2 0.1 -0.1 0.6 -1.1 0.0 -1.6 0.5 0.1 -0.7 -0.1 -0.0 -0.1 0.1 -0.2 -0.0 -0.2 -1.1 0.0 -1.2
Medication: Blood pressure 0.9 1.8 6.6 2.1 1.0 0.9 0.9 -0.1 1.8 0.0 1.9 1.2 0.9 1.8 0.4 0.8 0.8 0.9 0.9 0.9 -0.2 2.6 1.2 2.5
Pain type(s) experienced in last month: Hip pain 0.1 0.1 0.8 0.9 -0.2 -0.2 0.0 -0.6 0.2 0.0 -0.2 -0.3 -0.1 -0.2 -0.0 -0.0 -0.5 -0.1 -0.3 0.0 -0.3 -0.6 -0.2 -0.4
Supplements: Fish oil (including cod liver oil) 0.3 0.4 1.8 -0.9 -0.7 -0.7 -0.7 0.3 -0.7 0.0 -0.3 -0.1 -0.7 -1.3 -0.4 -0.7 -0.7 -0.6 -0.7 -0.6 0.7 -0.5 -0.5 -0.5
High cholesterol (Self-reported) 0.6 1.1 2.3 -1.4 -1.5 -1.3 -1.3 -0.5 -0.8 0.0 -1.5 -0.2 -1.3 -0.8 -0.9 -1.2 -1.1 -1.3 -1.1 -1.3 1.2 -0.4 -1.1 -0.4
Medication: Bendroflumethiazide 0.4 0.6 3.3 0.8 -0.1 -0.1 -0.2 -0.7 0.2 0.0 -0.7 0.9 -0.2 1.3 -0.1 -0.1 -0.5 -0.5 -0.4 -0.4 0.9 1.8 0.3 1.8
Medication: Paracetamol 0.3 0.5 3.1 -0.6 -0.4 -0.2 -0.3 -0.6 -0.3 0.0 -1.2 -0.3 -0.2 -0.7 0.1 -0.2 -0.4 -0.4 -0.4 -0.3 -0.2 -1.8 -0.4 -1.7
Medication: Lisinopril 0.2 0.3 1.1 1.0 0.6 0.4 0.4 -1.1 -0.4 0.0 -0.7 0.7 0.3 0.4 0.0 0.2 0.0 -0.0 0.3 0.2 0.1 1.0 0.4 0.9
Medication: Atorvastatin 1.9 2.4 3.6 -0.5 -1.8 -1.9 -1.9 -1.8 -1.7 0.0 -1.2 -1.4 -1.9 -0.9 -1.4 -1.5 -1.9 -1.8 -1.8 -1.6 1.4 -1.6 -1.5 -1.3
Illnesses of father: High blood pressure 0.3 0.3 3.3 1.8 0.6 0.3 0.4 -0.8 0.3 0.0 1.1 -0.1 0.4 -0.6 -0.3 0.2 0.2 0.2 0.2 0.6 -0.4 -0.0 0.4 -0.2
Alcohol drinker status: Never 2.6 3.1 6.6 2.6 1.7 2.0 2.0 2.1 1.7 0.0 0.7 1.1 1.8 0.4 1.8 2.0 1.8 2.2 1.9 2.2 -2.1 1.2 1.9 1.3
Ever smoked 2.4 4.2 8.7 -1.6 -2.4 -2.3 -2.4 -0.9 -1.2 0.0 -0.8 -0.9 -2.5 -1.2 -2.4 -2.4 -2.8 -2.6 -2.7 -2.6 3.0 1.0 -2.3 1.3
Basal metabolic rate 0.1 0.8 2.7 0.1 0.9 0.8 0.8 1.4 0.7 0.0 1.0 0.8 0.8 1.6 1.0 0.8 0.7 1.0 0.8 0.9 -0.8 0.3 0.9 0.5
Leg fat percentage (left) 0.7 2.4 4.2 -1.6 -2.0 -1.9 -1.9 -1.8 -0.6 0.0 -1.0 -0.9 -1.9 -0.2 -1.7 -2.0 -1.9 -1.9 -1.8 -2.0 2.0 -0.1 -1.8 0.0
Arm fat-free mass (left) 0.2 1.0 2.5 0.2 1.0 0.9 1.0 1.6 0.8 0.0 1.2 1.1 0.9 1.6 1.2 1.0 0.8 1.1 0.9 1.1 -0.8 0.6 1.1 0.8
Number of operations (self-reported) 0.5 0.8 2.2 0.2 -0.7 -0.8 -0.8 -0.2 0.5 0.0 0.5 -1.2 -1.0 0.2 -0.9 -0.9 -1.0 -0.8 -0.8 -0.9 1.3 1.4 -0.7 1.5
Average weekly beer plus cider intake 0.1 0.1 0.4 0.6 0.4 0.3 0.3 0.1 0.6 0.0 -0.3 0.6 0.5 0.0 0.0 0.1 0.1 0.3 0.1 -0.0 -0.1 -0.4 0.3 -0.7
Irritability 2.3 3.9 8.4 -0.4 -2.6 -2.3 -2.3 -2.9 -0.7 0.0 -1.1 -0.6 -2.4 -2.1 -2.2 -2.4 -2.3 -2.3 -2.2 -2.4 2.3 -0.9 -2.4 -0.7
Risk taking 1.8 2.7 6.7 1.6 1.5 1.3 1.5 2.0 2.2 0.0 1.8 -0.4 1.4 2.6 2.0 1.5 1.5 1.4 1.4 1.3 -1.8 1.9 1.3 2.2
Ever had prostate specific antigen (PSA) test 0.5 0.6 1.9 -1.4 -0.7 -0.6 -0.7 0.3 -1.3 0.0 -1.2 -0.6 -0.6 0.1 -0.6 -0.6 -0.3 -0.4 -0.4 -0.9 1.1 0.8 -0.8 0.8
Fractured/broken bones in last 5 years 0.1 0.1 1.3 1.2 -0.0 0.0 0.1 -0.3 -0.3 0.0 -0.5 0.4 0.1 0.8 -0.3 0.1 0.1 -0.1 -0.0 0.0 -0.4 0.2 -0.1 0.2
Age started oral contraceptive pill 0.3 0.4 1.6 0.1 -0.5 -0.5 -0.5 0.3 0.1 0.0 -0.6 0.3 -0.5 -0.4 -0.8 -0.7 -0.4 -0.3 -0.5 -0.5 0.9 1.2 -0.6 1.1
Diastolic blood pressure, automated reading 0.6 2.0 6.9 1.4 1.0 0.8 1.1 2.0 2.3 0.0 2.6 0.7 1.0 2.4 1.6 1.0 1.4 1.1 1.4 0.7 -0.8 1.2 1.1 1.2
Ever depressed for a whole week 1.1 1.4 5.9 -0.0 -1.1 -0.8 -0.9 -2.1 -2.4 0.0 -2.1 1.0 -0.7 -0.7 -0.7 -0.9 -0.9 -0.9 -0.9 -1.0 1.0 -1.1 -0.9 -1.4
Unable to work because of sickness or disability 3.0 3.9 7.9 -1.8 -2.3 -2.3 -2.3 -1.7 -0.4 0.0 -0.6 -1.5 -2.4 -0.0 -2.5 -2.4 -2.4 -2.5 -2.3 -2.7 2.8 0.9 -2.2 1.0
Commuting to job workplace: Cycle 0.3 0.4 1.7 -0.2 0.2 0.3 0.3 -0.3 -0.5 0.0 -0.4 1.3 0.5 1.2 0.6 0.3 0.2 0.3 0.3 0.2 -0.5 -1.1 0.3 -1.3
Myopia 0.3 0.5 4.0 -2.0 -0.1 -0.1 -0.1 0.8 -0.1 0.0 0.7 -0.8 -0.1 -1.8 0.2 -0.3 -0.2 0.2 -0.2 0.1 -0.0 -0.4 -0.0 -0.4
Vascular/heart problems diagnosed by doctor 0.5 1.2 5.6 -2.4 -0.4 -0.6 -0.6 -0.4 -0.1 0.0 -0.7 -1.5 -0.6 -1.9 -0.1 -0.6 -0.5 -0.5 -0.6 -0.5 -0.1 -2.4 -0.9 -2.2
Cholesterol lowering medication 0.6 0.9 1.8 -1.1 -1.2 -1.1 -1.1 -0.7 -0.4 0.0 -0.2 -0.2 -1.0 -0.4 -1.0 -1.1 -1.0 -0.9 -0.9 -1.2 1.0 -1.3 -0.8 -1.2
Medication: Omeprazole (e.g. Zanprol) 0.9 1.1 6.0 -0.7 -0.8 -0.7 -0.8 -0.7 -0.4 0.0 -0.3 -0.2 -0.9 0.2 -1.0 -0.8 -0.6 -0.6 -0.5 -1.2 1.5 2.4 -0.6 2.5
Pain experienced in last month 0.2 0.4 2.6 -1.1 -0.3 -0.3 -0.4 0.3 0.3 0.0 1.6 -0.3 -0.2 -1.2 -0.2 -0.3 0.1 -0.5 -0.2 -0.1 0.5 -0.7 -0.6 -0.8
Supplements: Calcium 0.2 0.2 1.9 0.4 -0.3 -0.2 -0.2 -1.4 -0.4 0.0 -0.8 0.2 -0.2 0.0 -0.3 -0.1 -0.1 -0.1 -0.2 -0.3 0.2 -0.3 -0.1 -0.4
Basal cell carcinoma (self-reported) 0.2 0.3 1.2 0.7 0.3 0.2 0.3 0.4 0.6 0.0 0.9 -0.6 0.2 0.0 0.3 0.4 0.3 0.5 0.4 0.3 -0.3 0.8 0.2 1.1
Heart attack/myocardial infarction (self-reported) 0.3 0.3 0.9 0.2 -0.5 -0.5 -0.6 -0.1 0.5 0.0 0.5 -0.6 -0.6 -0.6 -1.0 -0.5 -0.7 -0.5 -0.6 -0.5 0.7 0.9 -0.4 0.9
Deep venous thrombosis (DVT) (self-reported) 0.5 0.6 2.9 0.9 1.0 0.5 0.7 1.4 -0.3 0.0 0.8 -1.7 0.5 -0.2 0.7 0.7 0.6 0.8 0.8 0.7 -1.1 -0.6 0.4 -0.2
Heart disease (siblings) 0.1 0.2 0.8 -0.8 0.2 0.2 0.2 -0.1 0.7 0.0 0.9 0.6 0.2 0.2 -0.0 0.4 0.4 0.1 0.4 -0.1 -0.1 -0.6 0.1 -0.7
Alcohol drinker status: Previous 0.1 0.1 1.4 0.0 -0.3 -0.2 -0.2 -0.2 0.4 0.0 1.2 -0.4 -0.4 0.2 -0.1 -0.1 0.2 -0.1 0.1 -0.4 0.4 0.5 -0.0 0.5
Pack years of smoking 0.7 1.1 2.8 0.5 -1.3 -1.1 -1.1 -0.4 0.4 0.0 -0.5 -0.4 -1.0 -1.0 -1.7 -1.5 -1.4 -1.1 -1.4 -1.2 1.5 -0.4 -1.2 -0.6
Impedance of whole body 0.6 2.8 4.8 -1.4 -2.1 -1.8 -1.8 -2.2 -1.2 0.0 -1.7 -1.1 -1.7 -1.9 -2.1 -1.9 -1.6 -2.0 -1.9 -2.1 1.7 -0.4 -2.1 -0.6
Leg fat mass (left) 0.3 1.1 1.9 -1.3 -1.4 -1.3 -1.3 -1.0 -0.2 0.0 -0.4 -0.5 -1.3 0.4 -1.0 -1.4 -1.3 -1.2 -1.2 -1.4 1.3 -0.0 -1.1 0.1
Arm predicted mass (left) 0.2 1.2 3.7 0.5 1.2 1.0 1.1 1.5 0.8 0.0 1.0 1.2 1.0 1.9 1.5 1.1 0.9 1.2 1.1 1.2 -1.0 0.6 1.3 0.8