Hub : Traits :

Commuting to job workplace: Car/motor vehicle

1 significantly associated models · 1 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 179566296 180095451 1 1 5.9e-08 0.00011 0.57 98 TOR1AIP2

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder or Schizophrenia 2.25 1 0 0.0 0 1 TOR1AIP2
Schizophrenia (2018) 3.13 1 0 0.0 0 1 TOR1AIP2
Major Depression (MDD) 5.62 1 0 0.0 0 1 TOR1AIP2
Blood Eosinophil Count 1.12 1 0 0.0 0 1 TOR1AIP2
Blood Platelet Count 0.46 1 0 0.0 0 1 TOR1AIP2
Blood Red Count 1.57 1 0 0.0 0 1 TOR1AIP2
BMI 1.09 1 0 0.0 0 1 TOR1AIP2
Smoking Status 2.60 1 0 0.0 0 1 TOR1AIP2
Type 2 Diabetes (T2D) (2018) 3.61 1 0 0.0 0 1 TOR1AIP2
Lung FVC 0.77 1 0 0.0 0 1 TOR1AIP2
Chronotype (morning person) 12.49 1 1 2.2 0 1 TOR1AIP2
Relative age of first facial hair 3.53 1 0 0.0 0 1 TOR1AIP2
Trunk fat percentage 1.85 1 0 0.0 0 1 TOR1AIP2
Age when periods started (menarche) 3.31 1 0 0.0 0 1 TOR1AIP2
Qualifications: CSEs or equivalent 5.55 1 0 0.0 0 1 TOR1AIP2
Hayfever, allergic rhinitis or eczema 3.77 1 0 0.0 0 1 TOR1AIP2
Body mass index (BMI) 1.09 1 0 0.0 0 1 TOR1AIP2
Trunk fat mass 1.56 1 0 0.0 0 1 TOR1AIP2
Waist circumference 1.10 1 0 0.0 0 1 TOR1AIP2
Nervous feelings 3.14 1 0 0.0 0 1 TOR1AIP2
Hair/balding pattern: Pattern 2 3.67 1 0 0.0 0 1 TOR1AIP2
Allergy 3.06 1 0 0.0 0 1 TOR1AIP2
Diabetes (self-reported) 3.98 1 0 0.0 0 1 TOR1AIP2
Fluid intelligence score 2.56 1 0 0.0 0 1 TOR1AIP2
Arm fat percentage (right) 1.41 1 0 0.0 0 1 TOR1AIP2
Time employed in main current job 8.76 1 0 0.0 0 1 TOR1AIP2
Falls in the last year 4.13 1 0 0.0 0 1 TOR1AIP2
Medication: Cholesterol lowering 3.00 1 0 0.0 0 1 TOR1AIP2
Arm fat mass (right) 1.29 1 0 0.0 0 1 TOR1AIP2
Exposure to tobacco smoke at home 6.26 1 0 0.0 0 1 TOR1AIP2
Breastfed as a baby 3.27 1 0 0.0 0 1 TOR1AIP2
Body fat percentage 1.70 1 0 0.0 0 1 TOR1AIP2
Comparative body size at age 10 2.88 1 0 0.0 0 1 TOR1AIP2
Wheeze or whistling in the chest in last year 3.26 1 0 0.0 0 1 TOR1AIP2
Whole body fat mass 1.71 1 0 0.0 0 1 TOR1AIP2
Illnesses of father: Heart disease 3.52 1 0 0.0 0 1 TOR1AIP2
Arm fat percentage (left) 1.49 1 0 0.0 0 1 TOR1AIP2
Long-standing illness, disability or infirmity 6.45 1 0 0.0 0 1 TOR1AIP2
Ever had stillbirth, spontaneous miscarriage or termination 4.95 1 0 0.0 0 1 TOR1AIP2
Commuting to job workplace: Walk 9.38 1 0 0.0 0 1 TOR1AIP2
Eye problems/disorders: Cataract 3.35 1 0 0.0 0 1 TOR1AIP2
Osteoporosis (self-reported) 5.25 1 0 0.0 0 1 TOR1AIP2
Osteoarthritis (self-reported) 3.40 1 0 0.0 0 1 TOR1AIP2
Arm fat mass (left) 1.27 1 0 0.0 0 1 TOR1AIP2
Hearing aid user 8.02 1 0 0.0 0 1 TOR1AIP2
Commuting to job workplace: Public transport 5.79 1 0 0.0 0 1 TOR1AIP2
Age started oral contraceptive pill 5.36 1 0 0.0 0 1 TOR1AIP2
Diastolic blood pressure, automated reading 2.05 1 0 0.0 0 1 TOR1AIP2
Ever depressed for a whole week 5.69 1 0 0.0 0 1 TOR1AIP2
Heart disease (siblings) 4.02 1 0 0.0 0 1 TOR1AIP2

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 0 0.000 1.2
GTEx Adipose Visceral Omentum 0 0.000 1.2
GTEx Adrenal Gland 0 0.000 1.2
GTEx Artery Aorta 0 0.000 1.2
GTEx Artery Coronary 0 0.000 1.3
GTEx Artery Tibial 0 0.000 1.1
GTEx Brain Caudate basal ganglia 0 0.000 1.1
GTEx Brain Cerebellar Hemisphere 0 0.000 1.2
GTEx Brain Cerebellum 0 0.000 1.3
GTEx Brain Cortex 0 0.000 1.1
GTEx Brain Frontal Cortex BA9 0 0.000 1.2
GTEx Brain Hippocampus 0 0.000 1.1
GTEx Brain Hypothalamus 0 0.000 1.3
GTEx Brain Nucleus accumbens basal ganglia 0 0.000 1.1
GTEx Brain Putamen basal ganglia 0 0.000 1.1
GTEx Breast Mammary Tissue 0 0.000 1.2
GTEx Breast Mammary Tissue (Male) 0 0.000 1.1
GTEx Breast Mammary Tissue (Female) 0 0.000 1.2
GTEx Cells EBV-transformed lymphocytes 0 0.000 1.2
GTEx Cells Transformed fibroblasts 0 0.000 1.1
GTEx Colon Sigmoid 0 0.000 1.2
GTEx Colon Transverse 0 0.000 1.1
GTEx Esophagus Gastroesophageal Junction 0 0.000 1.3
GTEx Esophagus Mucosa 0 0.000 1.2
GTEx Esophagus Muscularis 0 0.000 1.2
GTEx Heart Atrial Appendage 0 0.000 1.2
GTEx Heart Left Ventricle 0 0.000 1.2
GTEx Liver 0 0.000 1.2
GTEx Lung 0 0.000 1.2
GTEx Muscle Skeletal 0 0.000 1.1
GTEx Nerve Tibial 0 0.000 1.1
GTEx Ovary 0 0.000 1.2
GTEx Pancreas 0 0.000 1.2
GTEx Pituitary 0 0.000 1.2
GTEx Prostate 0 0.000 1.3
GTEx Skin Not Sun Exposed Suprapubic 0 0.000 1.1
GTEx Skin Sun Exposed Lower leg 0 0.000 1.1
GTEx Small Intestine Terminal Ileum 0 0.000 1.2
GTEx Spleen 0 0.000 1.2
GTEx Stomach 0 0.000 1.2
GTEx Testis 0 0.000 1.1
GTEx Thyroid 0 0.000 1.1
GTEx Uterus 0 0.000 1.1
GTEx Vagina 0 0.000 1.2
GTEx Whole Blood 0 0.000 1.2
METSIM Adipose 0 0.000 1.1
NTR Blood 0 0.000 1.2
ROSMAP Brain Pre-frontal Cortex 0 0.000 1.2
YFS Blood 0 0.000 1.2
CommonMind Brain Pre-frontal Cortex 0 0.000 1.1
The Cancer Genome Atlas Bladder Urothelial Carcinoma 0 0.000 1.0
The Cancer Genome Atlas Breast Invasive Carcinoma 1 0.023 1.1
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 0 0.000 1.1
The Cancer Genome Atlas Colon Adenocarcinoma 0 0.000 1.1
The Cancer Genome Atlas Esophageal Carcinoma 0 0.000 1.1
The Cancer Genome Atlas Glioblastoma Multiforme 0 0.000 1.2
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 0 0.000 1.1
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 0 0.000 1.1
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 0 0.000 1.1
The Cancer Genome Atlas Brain Lower Grade Glioma 0 0.000 1.2
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 0 0.000 1.0
The Cancer Genome Atlas Lung Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 0 0.000 1.1
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 0 0.000 1.1
The Cancer Genome Atlas Pancreatic Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 0 0.000 1.2
The Cancer Genome Atlas Prostate Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Rectum Adenocarcinoma 0 0.000 1.1
The Cancer Genome Atlas Soft Tissue Sarcoma 0 0.000 1.1
The Cancer Genome Atlas Skin Cutaneous Melanoma 0 0.000 1.1
The Cancer Genome Atlas Stomach Adenocarcinoma 0 0.000 1.2
The Cancer Genome Atlas Testicular Germ Cell Tumors 0 0.000 1.0
The Cancer Genome Atlas Thyroid Carcinoma 0 0.000 1.2
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 0 0.000 1.1