[Hub]/) : Traits : Waist Hip Ratio (WHR) : ← →

chr16:66,542,957-69,084,178

Best TWAS P=7.37e-12 · Best GWAS P=1.15e-11 conditioned to 0.898

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	ATP6V0D1	0.10	0.12	lasso	8	0.11	2.4e-13	-5.1	6.2	7.4e-10	-0.85	0.10	0.90	FALSE
2	GTEx	Adipose Subcutaneous	RANBP10	0.05	0.01	lasso	6	0.01	3.5e-02	-5.7	5.9	3.5e-09	-0.81	0.20	0.68	FALSE
3	GTEx	Artery Tibial	RANBP10	0.08	0.04	lasso	3	0.05	6.4e-05	-6.6	6.8	1.0e-11	-0.91	0.08	0.91	FALSE
4	GTEx	Brain Cerebellar Hemisphere	ELMO3	0.60	0.48	lasso	3	0.51	4.8e-15	-5.9	5.4	8.8e-08	-0.16	0.79	0.21	FALSE
5	GTEx	Brain Cerebellum	PRMT7	0.37	0.16	enet	25	0.23	2.2e-07	3.0	-5.2	2.5e-07	0.25	0.35	0.38	FALSE
6	GTEx	Brain Nucleus accumbens basal ganglia	CTCF	0.11	0.03	lasso	5	0.04	2.4e-02	-6.2	-5.8	7.5e-09	0.73	0.08	0.44	FALSE
7	GTEx	Esophagus Mucosa	SLC7A6	0.09	0.00	enet	12	0.00	1.4e-01	-3.8	5.1	2.8e-07	-0.16	0.13	0.12	TRUE
8	GTEx	Esophagus Muscularis	RANBP10	0.13	0.05	lasso	4	0.02	2.3e-02	-6.7	6.8	1.2e-11	-0.88	0.04	0.94	FALSE
9	GTEx	Muscle Skeletal	C16orf86	0.05	0.04	lasso	2	0.03	4.0e-04	-6.3	6.4	1.4e-10	-0.80	0.08	0.66	FALSE
10	GTEx	Nerve Tibial	RANBP10	0.15	0.14	lasso	7	0.13	1.8e-09	-6.5	6.8	8.1e-12	-0.87	0.12	0.88	FALSE
11	GTEx	Pituitary	ZDHHC1	0.23	0.13	lasso	4	0.08	4.0e-03	-6.3	-6.2	5.3e-10	0.73	0.05	0.44	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	CTRL	0.13	0.04	lasso	9	0.08	2.7e-05	-5.8	-5.4	7.3e-08	0.68	0.22	0.74	FALSE
13	GTEx	Spleen	ATP6V0D1	0.36	0.03	enet	9	0.07	6.0e-03	-3.7	6.2	5.3e-10	-0.84	0.02	0.47	FALSE
14	GTEx	Testis	DUS2	0.15	0.01	enet	9	0.03	1.1e-02	1.0	5.1	2.6e-07	-0.60	0.10	0.69	FALSE
15	GTEx	Thyroid	RANBP10	0.08	0.03	lasso	4	0.03	2.2e-03	-5.8	6.3	2.4e-10	-0.87	0.12	0.56	FALSE
16	GTEx	Thyroid	ZDHHC1	0.07	0.03	lasso	6	0.02	1.6e-02	-6.5	-6.4	1.6e-10	0.97	0.06	0.83	FALSE
17	GTEx	Thyroid	HSD11B2	0.15	0.07	enet	23	0.09	1.9e-07	-5.8	-6.9	7.4e-12	0.88	0.17	0.83	TRUE
18	GTEx	Whole Blood	ATP6V0D1	0.08	0.00	enet	13	0.00	3.6e-01	-5.2	6.5	6.4e-11	-0.84	0.02	0.90	FALSE
19	GTEx	Whole Blood	DUS2	0.12	0.04	enet	10	0.05	4.0e-05	-6.3	-6.3	3.5e-10	0.74	0.04	0.96	FALSE
20	METSIM	Adipose	CTCF	0.03	0.02	bslmm	222	0.01	3.4e-03	-6.4	-5.6	2.6e-08	0.90	0.02	0.90	FALSE
21	METSIM	Adipose	LRRC36	0.10	0.07	lasso	24	0.10	1.6e-14	-6.4	-6.5	9.5e-11	0.93	0.02	0.98	FALSE
22	METSIM	Adipose	NFATC3	0.03	0.00	blup	298	0.00	3.4e-01	3.9	5.9	3.3e-09	-0.50	0.04	0.47	FALSE
23	METSIM	Adipose	RLTPR	0.04	0.00	bslmm	211	0.00	1.1e-01	-6.4	-6.0	2.0e-09	0.83	0.03	0.80	FALSE
24	NTR	Blood	ATP6V0D1	0.02	0.01	bslmm	220	0.01	1.6e-04	-5.1	6.3	3.4e-10	-0.74	0.12	0.79	FALSE
25	YFS	Blood	ATP6V0D1	0.14	0.18	lasso	15	0.20	1.8e-63	-6.8	6.6	5.3e-11	-0.94	0.02	0.98	FALSE
26	YFS	Blood	DUS2L	0.19	0.23	enet	28	0.28	3.8e-91	-2.5	-5.1	2.7e-07	0.59	1.00	0.00	FALSE
27	YFS	Blood	ZDHHC1	0.05	0.05	enet	26	0.05	1.8e-16	-6.7	-6.8	1.5e-11	0.88	0.02	0.98	FALSE
28	The Cancer Genome Atlas	Breast Invasive Carcinoma	ZDHHC1	0.02	0.01	lasso	1	0.01	2.4e-03	-6.4	6.4	2.1e-10	-0.97	0.02	0.70	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	CENPT	0.05	0.05	enet	8	0.04	3.0e-03	-5.8	-5.3	1.1e-07	0.71	0.01	0.90	FALSE
30	The Cancer Genome Atlas	Esophageal Carcinoma	CENPT	0.13	0.00	blup	33	0.00	3.5e-01	-4.0	-5.9	3.7e-09	0.65	0.01	0.34	FALSE
31	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	GFOD2	0.03	0.03	lasso	1	0.03	3.6e-04	-5.8	5.8	7.4e-09	-0.75	0.01	0.98	FALSE
32	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	ATP6V0D1	0.04	0.06	lasso	4	0.05	1.4e-06	-5.2	5.4	5.3e-08	-0.74	0.23	0.76	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TPPP3	0.03	0.02	blup	31	0.04	2.1e-05	-6.6	6.4	1.9e-10	-0.94	0.03	0.96	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	LRRC36	0.07	0.03	blup	39	0.03	2.5e-04	-6.7	-5.8	5.7e-09	0.90	0.01	0.99	FALSE
35	The Cancer Genome Atlas	Brain Lower Grade Glioma	RANBP10	0.04	0.03	blup	31	0.04	6.5e-05	-5.8	5.9	4.3e-09	-0.74	0.05	0.90	FALSE
36	The Cancer Genome Atlas	Lung Adenocarcinoma	ATP6V0D1	0.04	0.02	blup	33	0.03	4.7e-04	-5.1	6.2	5.4e-10	-0.88	0.02	0.96	FALSE
37	The Cancer Genome Atlas	Lung Adenocarcinoma	C16orf86	0.04	0.04	lasso	2	0.03	3.8e-04	-6.2	6.0	1.7e-09	-0.79	0.00	0.99	FALSE
38	The Cancer Genome Atlas	Lung Adenocarcinoma	RLTPR	0.03	0.02	lasso	3	0.02	1.8e-03	-4.7	5.3	1.1e-07	-0.80	0.00	0.84	FALSE
39	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ATP6V0D1	0.04	0.00	enet	6	0.00	9.3e-02	-5.2	5.2	2.6e-07	-0.70	0.01	0.50	FALSE
40	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NFATC3	0.23	0.05	enet	17	0.06	1.5e-03	-6.2	5.7	1.6e-08	-0.50	0.00	0.80	FALSE
41	The Cancer Genome Atlas	Prostate Adenocarcinoma	C16orf86	0.05	0.05	lasso	1	0.04	2.9e-05	-6.2	6.2	6.1e-10	-0.79	0.00	1.00	FALSE
42	The Cancer Genome Atlas	Prostate Adenocarcinoma	CENPT	0.02	0.01	blup	33	0.01	6.9e-02	-5.8	-5.6	2.0e-08	0.72	0.02	0.71	FALSE
43	The Cancer Genome Atlas	Rectum Adenocarcinoma	LRRC36	0.13	0.12	lasso	14	0.11	1.4e-03	-6.4	-6.4	1.3e-10	0.96	0.01	0.67	FALSE
44	The Cancer Genome Atlas	Stomach Adenocarcinoma	AGRP	0.04	0.02	blup	23	0.03	3.0e-03	-6.7	-6.0	1.5e-09	0.88	0.00	0.76	FALSE
45	The Cancer Genome Atlas	Thyroid Carcinoma	LRRC36	0.04	0.04	lasso	3	0.04	1.5e-04	-6.5	-6.5	1.0e-10	0.97	0.03	0.96	FALSE
46	The Cancer Genome Atlas	Thyroid Carcinoma	ZDHHC1	0.07	0.06	enet	7	0.07	2.9e-07	-6.6	-6.6	3.8e-11	0.96	0.02	0.98	FALSE