Best TWAS P=8.16e-09 · Best GWAS P=1.6e-11 conditioned to 3.84e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SDK1 | 0.18 | 0.12 | lasso | 8 | 0.14 | 9.4e-12 | -5.4 | 5.2 | 2.6e-07 | 0.42 | 0.52 | 0.48 | FALSE |
| 2 | GTEx | Esophagus Muscularis | SDK1 | 0.08 | 0.03 | lasso | 5 | 0.02 | 1.1e-02 | -5.8 | 5.8 | 8.2e-09 | 0.45 | 0.18 | 0.77 | TRUE |
| 3 | GTEx | Muscle Skeletal | SDK1 | 0.13 | 0.02 | lasso | 4 | 0.03 | 1.4e-03 | -5.4 | 5.5 | 3.7e-08 | 0.43 | 0.29 | 0.70 | FALSE |