Best TWAS P=4.42e-09 · Best GWAS P=3.76e-08 conditioned to 0.0751
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Testis | USP35 | 0.07 | 0.06 | lasso | 2 | 0.07 | 0.00064 | -5.2 | -5.2 | 1.7e-07 | 0.93 | 0.05 | 0.91 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | GAB2 | 0.05 | 0.00 | blup | 435 | 0.02 | 0.00080 | -4.6 | 5.9 | 4.4e-09 | -0.73 | 0.15 | 0.78 | TRUE |
| 3 | The Cancer Genome Atlas | Stomach Adenocarcinoma | GAB2 | 0.04 | 0.04 | blup | 100 | 0.04 | 0.00140 | -4.8 | 5.2 | 2.0e-07 | -0.90 | 0.05 | 0.87 | FALSE |