[Hub]/) : Traits : Height :

chr4:6,213,622-11,156,010

Best TWAS P=4.68e-34 · Best GWAS P=1.59e-52 conditioned to 7.53e-14

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC2A9 0.06 0.01 blup 565 0.02 6.2e-04 -5.0 -6.9 3.8e-12 0.04 0.48 0.08 TRUE
2 GTEx Adipose Subcutaneous TRMT44 0.20 0.19 lasso 8 0.19 9.4e-16 -7.3 -5.4 7.2e-08 -0.04 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum SLC2A9 0.15 0.02 lasso 4 0.04 3.6e-03 -5.7 -6.5 6.3e-11 0.04 0.29 0.12 FALSE
4 GTEx Adipose Visceral Omentum TRMT44 0.11 0.11 lasso 2 0.08 9.2e-05 -5.5 -5.4 8.5e-08 0.02 0.86 0.01 FALSE
5 GTEx Adrenal Gland ACOX3 0.15 0.12 lasso 6 0.13 2.5e-05 -6.9 -6.9 6.9e-12 0.07 0.70 0.02 FALSE
6 GTEx Artery Aorta TRMT44 0.11 0.11 lasso 4 0.10 6.4e-06 -5.5 -5.7 1.3e-08 0.03 0.86 0.02 FALSE
7 GTEx Artery Tibial TRMT44 0.10 0.06 lasso 6 0.06 1.6e-05 -5.5 -6.1 9.8e-10 0.06 0.94 0.00 FALSE
8 GTEx Brain Caudate basal ganglia TRMT44 0.51 0.30 lasso 9 0.26 3.4e-08 -5.4 -5.5 4.3e-08 0.02 0.93 0.01 FALSE
9 GTEx Brain Cerebellar Hemisphere TRMT44 0.41 0.26 lasso 5 0.20 5.8e-06 -7.3 -7.2 4.2e-13 0.08 0.79 0.01 FALSE
10 GTEx Brain Cerebellar Hemisphere AFAP1 0.60 0.28 lasso 11 0.34 1.1e-09 9.3 8.5 2.5e-17 -0.01 0.02 0.98 FALSE
11 GTEx Brain Cerebellar Hemisphere RP11-689P11.2 0.45 0.14 lasso 5 0.19 1.4e-05 -7.3 -6.0 2.3e-09 0.05 0.52 0.04 FALSE
12 GTEx Brain Cerebellar Hemisphere AFAP1-AS1 0.33 0.16 lasso 7 0.16 5.9e-05 9.3 9.0 1.9e-19 0.00 0.02 0.93 TRUE
13 GTEx Brain Cerebellum GRPEL1 0.37 0.17 lasso 8 0.13 9.7e-05 -6.0 -5.8 5.7e-09 0.07 0.22 0.30 FALSE
14 GTEx Brain Cerebellum TRMT44 0.48 0.16 lasso 10 0.18 4.4e-06 -5.4 -5.2 2.6e-07 0.03 0.58 0.06 FALSE
15 GTEx Brain Cerebellum AFAP1 0.47 0.19 lasso 4 0.19 2.8e-06 -6.1 8.6 7.9e-18 0.00 0.03 0.95 FALSE
16 GTEx Brain Cerebellum RP11-689P11.2 0.28 0.11 lasso 2 0.17 1.0e-05 -7.3 -5.2 2.0e-07 0.07 0.18 0.18 FALSE
17 GTEx Brain Cerebellum AFAP1-AS1 0.47 0.05 lasso 10 0.10 7.6e-04 3.5 7.8 4.2e-15 0.01 0.04 0.72 FALSE
18 GTEx Brain Cortex TRMT44 0.29 0.22 enet 20 0.24 3.2e-07 -7.3 -6.2 5.3e-10 0.00 0.62 0.04 FALSE
19 GTEx Brain Frontal Cortex BA9 RP11-689P11.2 0.28 0.03 lasso 4 0.12 4.1e-04 -5.7 -5.7 1.3e-08 0.07 0.20 0.05 FALSE
20 GTEx Brain Hypothalamus SLC2A9 0.42 -0.01 enet 39 0.03 6.9e-02 -5.7 -6.1 1.0e-09 0.07 0.07 0.11 FALSE
21 GTEx Brain Hypothalamus TRMT44 0.38 0.19 lasso 5 0.13 6.1e-04 -7.5 -6.7 2.7e-11 0.05 0.46 0.03 FALSE
22 GTEx Brain Nucleus accumbens basal ganglia TRMT44 0.25 0.19 lasso 5 0.17 2.1e-05 -7.3 -6.9 4.4e-12 0.08 0.40 0.03 FALSE
23 GTEx Breast Mammary Tissue TRMT44 0.19 0.22 lasso 5 0.20 2.2e-10 -7.2 -6.9 6.3e-12 0.07 1.00 0.00 FALSE
24 GTEx Breast Mammary Tissue (Male) TRMT44 0.22 0.03 lasso 8 0.01 2.1e-01 -5.7 -6.5 9.2e-11 0.10 0.07 0.06 FALSE
25 GTEx Breast Mammary Tissue (Female) TRMT44 0.23 0.19 enet 12 0.19 2.5e-06 -7.2 -5.1 3.1e-07 0.02 0.67 0.02 FALSE
26 GTEx Breast Mammary Tissue (Female) RP11-689P11.3 0.12 0.07 lasso 2 0.08 2.5e-03 -7.3 -6.6 3.6e-11 0.07 0.14 0.06 FALSE
27 GTEx Cells EBV-transformed lymphocytes GRPEL1 0.25 0.12 enet 7 0.06 3.9e-03 -5.9 -5.7 1.4e-08 0.05 0.24 0.37 FALSE
28 GTEx Cells EBV-transformed lymphocytes SLC2A9 0.25 0.18 lasso 6 0.18 2.0e-06 -5.0 -5.2 2.1e-07 0.05 0.86 0.06 FALSE
29 GTEx Cells EBV-transformed lymphocytes RP11-689P11.2 0.17 0.13 lasso 4 0.12 1.1e-04 -6.9 -6.5 8.3e-11 0.04 0.68 0.02 FALSE
30 GTEx Cells Transformed fibroblasts WDR1 0.09 0.03 lasso 4 0.03 2.1e-03 -4.5 5.2 2.3e-07 -0.06 0.29 0.03 FALSE
31 GTEx Cells Transformed fibroblasts ACOX3 0.25 0.14 lasso 7 0.14 1.6e-10 -7.3 -7.6 3.5e-14 0.08 1.00 0.00 FALSE
32 GTEx Cells Transformed fibroblasts GRPEL1 0.27 0.13 lasso 9 0.18 2.3e-13 -4.8 -5.6 2.5e-08 0.05 0.64 0.36 FALSE
33 GTEx Cells Transformed fibroblasts AFAP1 0.26 0.10 enet 39 0.13 3.6e-10 -4.9 -6.6 5.3e-11 -0.02 0.01 0.99 FALSE
34 GTEx Cells Transformed fibroblasts AFAP1-AS1 0.20 0.09 enet 31 0.07 4.7e-06 -9.8 -6.7 2.1e-11 -0.05 0.00 1.00 FALSE
35 GTEx Colon Transverse TRMT44 0.17 0.05 lasso 5 0.02 4.4e-02 -7.2 -6.9 7.1e-12 0.09 0.24 0.04 FALSE
36 GTEx Esophagus Gastroesophageal Junction RP11-689P11.2 0.30 0.21 lasso 7 0.25 1.2e-09 -6.6 -6.5 8.9e-11 0.07 0.99 0.00 FALSE
37 GTEx Esophagus Mucosa AFAP1 0.48 0.40 enet 29 0.43 3.9e-31 7.6 8.0 1.0e-15 -0.02 0.62 0.38 FALSE
38 GTEx Esophagus Mucosa RP11-689P11.2 0.21 0.12 lasso 7 0.11 6.4e-08 -6.9 -6.3 2.4e-10 0.04 1.00 0.00 FALSE
39 GTEx Esophagus Mucosa AFAP1-AS1 0.36 0.28 lasso 8 0.29 5.9e-20 7.6 7.4 1.1e-13 -0.02 0.51 0.49 FALSE
40 GTEx Esophagus Muscularis TRMT44 0.12 0.07 lasso 5 0.06 2.2e-04 -7.3 -6.5 5.9e-11 0.07 0.68 0.03 FALSE
41 GTEx Heart Atrial Appendage ZNF518B 0.10 0.01 lasso 3 0.00 4.6e-01 -5.9 6.2 5.2e-10 0.01 0.02 0.86 TRUE
42 GTEx Liver SLC2A9 0.18 0.13 lasso 6 0.12 3.7e-04 -5.8 -6.1 8.1e-10 0.00 0.30 0.13 FALSE
43 GTEx Lung ACOX3 0.13 0.03 lasso 5 0.05 6.3e-05 -7.3 -5.7 1.4e-08 0.06 0.89 0.00 FALSE
44 GTEx Lung SLC2A9 0.06 0.00 lasso 5 0.00 5.7e-01 -5.4 -6.7 2.4e-11 0.04 0.35 0.06 FALSE
45 GTEx Lung TRMT44 0.13 0.10 lasso 6 0.08 1.3e-06 -4.6 -5.8 6.3e-09 0.05 0.99 0.00 FALSE
46 GTEx Lung RP11-689P11.2 0.22 0.18 lasso 5 0.21 6.4e-16 -4.5 -6.0 1.7e-09 0.04 1.00 0.00 FALSE
47 GTEx Muscle Skeletal GRPEL1 0.10 0.05 lasso 3 0.05 5.0e-06 -4.9 -5.2 2.3e-07 0.03 0.85 0.14 FALSE
48 GTEx Nerve Tibial GRPEL1 0.16 0.07 lasso 4 0.06 2.9e-05 -5.9 -5.1 2.7e-07 0.05 0.46 0.34 FALSE
49 GTEx Nerve Tibial TRMT44 0.27 0.26 lasso 5 0.27 5.4e-19 -7.3 -7.0 3.0e-12 0.08 1.00 0.00 FALSE
50 GTEx Nerve Tibial RP11-689P11.2 0.32 0.11 enet 19 0.28 1.1e-19 -4.5 -5.3 1.2e-07 0.04 1.00 0.00 FALSE
51 GTEx Nerve Tibial RP11-689P11.3 0.17 0.10 lasso 4 0.08 3.3e-06 -5.5 -5.5 4.7e-08 0.02 0.94 0.00 FALSE
52 GTEx Ovary TRMT44 0.33 0.32 lasso 3 0.29 6.2e-08 -6.6 -7.0 2.7e-12 0.05 0.83 0.01 FALSE
53 GTEx Ovary RP11-689P11.2 0.34 0.10 lasso 6 0.04 3.7e-02 -4.5 -5.5 3.5e-08 0.01 0.15 0.05 FALSE
54 GTEx Pancreas SLC2A9 0.20 0.00 enet 16 0.03 1.5e-02 -5.6 -5.9 3.4e-09 0.01 0.22 0.21 FALSE
55 GTEx Pituitary RP11-689P11.2 0.56 0.05 lasso 8 0.12 6.5e-04 -7.5 -6.0 2.4e-09 0.04 0.45 0.08 FALSE
56 GTEx Skin Not Sun Exposed Suprapubic AFAP1 0.47 0.46 lasso 4 0.45 2.8e-27 7.6 7.7 1.6e-14 -0.02 0.98 0.02 FALSE
57 GTEx Skin Not Sun Exposed Suprapubic AFAP1-AS1 0.33 0.30 lasso 6 0.29 4.0e-16 7.6 7.5 5.9e-14 -0.03 0.98 0.02 FALSE
58 GTEx Skin Sun Exposed Lower leg SLC2A9 0.18 0.03 enet 15 0.06 1.2e-05 -5.9 -6.7 2.2e-11 -0.01 0.28 0.54 FALSE
59 GTEx Skin Sun Exposed Lower leg TBC1D14 0.11 0.08 lasso 2 0.07 1.5e-06 -6.0 -5.2 1.9e-07 0.05 0.24 0.70 FALSE
60 GTEx Skin Sun Exposed Lower leg TRMT44 0.08 0.04 lasso 4 0.02 1.7e-02 -7.5 -6.6 4.7e-11 0.06 0.48 0.02 FALSE
61 GTEx Skin Sun Exposed Lower leg AFAP1 0.50 0.45 lasso 8 0.46 4.2e-42 7.6 7.5 9.2e-14 -0.02 1.00 0.00 FALSE
62 GTEx Skin Sun Exposed Lower leg AFAP1-AS1 0.34 0.26 lasso 5 0.24 8.3e-20 7.6 7.6 3.7e-14 -0.01 0.77 0.23 FALSE
63 GTEx Whole Blood AFAP1 0.45 0.48 enet 44 0.50 1.3e-52 7.6 7.2 4.1e-13 -0.01 0.98 0.02 FALSE
64 GTEx Whole Blood AFAP1-AS1 0.36 0.33 lasso 8 0.33 2.6e-31 7.6 7.8 4.4e-15 -0.01 0.48 0.52 FALSE
65 METSIM Adipose AFAP1 0.05 0.03 enet 13 0.03 1.3e-05 7.6 8.2 3.7e-16 -0.01 0.04 0.96 FALSE
66 METSIM Adipose RP11-689P11.2 0.14 0.16 enet 25 0.17 4.2e-25 -7.2 -6.4 1.9e-10 0.05 1.00 0.00 FALSE
67 METSIM Adipose SLC2A9 0.05 0.04 lasso 4 0.03 9.3e-06 -5.7 -5.9 4.4e-09 0.00 0.67 0.33 FALSE
68 NTR Blood AFAP1 0.13 0.12 lasso 6 0.13 3.1e-39 7.6 6.4 1.2e-10 0.00 1.00 0.00 FALSE
69 NTR Blood TBC1D14 0.05 0.03 lasso 7 0.02 7.5e-08 -4.8 5.4 7.6e-08 0.00 0.66 0.34 FALSE
70 YFS Blood TADA2B 0.09 0.11 lasso 4 0.10 5.6e-32 -4.9 -5.2 1.7e-07 0.03 0.99 0.01 FALSE
71 The Cancer Genome Atlas Bladder Urothelial Carcinoma GPR78 0.07 0.00 blup 65 0.02 1.7e-02 9.9 -6.0 2.3e-09 0.44 0.00 0.57 FALSE
72 The Cancer Genome Atlas Breast Invasive Carcinoma FLJ36777 0.04 0.02 blup 71 0.03 2.4e-07 -5.8 5.7 1.4e-08 -0.04 0.01 0.99 FALSE
73 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma ZNF518B 0.08 0.04 lasso 2 0.01 1.2e-01 6.2 6.2 5.5e-10 0.02 0.02 0.28 FALSE
74 The Cancer Genome Atlas Colon Adenocarcinoma FLJ36777 0.06 0.00 blup 69 0.04 4.0e-03 -4.9 5.4 6.5e-08 -0.01 0.02 0.25 FALSE
75 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CPZ 0.03 0.00 blup 80 0.01 1.9e-02 -5.9 12.2 4.7e-34 -0.55 0.03 0.23 TRUE
76 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GRPEL1 0.09 0.10 blup 52 0.12 5.4e-13 -5.9 -5.6 2.7e-08 0.05 0.05 0.95 FALSE
77 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TADA2B 0.02 0.01 blup 56 0.02 1.9e-03 -6.0 -6.7 1.7e-11 0.06 0.05 0.61 TRUE
78 The Cancer Genome Atlas Brain Lower Grade Glioma GRPEL1 0.06 0.09 enet 9 0.10 3.1e-11 -4.8 -5.3 1.3e-07 0.04 0.18 0.82 FALSE
79 The Cancer Genome Atlas Brain Lower Grade Glioma SLC2A9 0.11 0.11 blup 206 0.13 1.0e-14 -5.4 -6.1 9.5e-10 0.06 0.07 0.93 FALSE
80 The Cancer Genome Atlas Lung Adenocarcinoma SLC2A9 0.06 0.02 enet 9 0.03 4.4e-04 -4.8 -5.5 3.4e-08 0.05 0.16 0.78 FALSE
81 The Cancer Genome Atlas Lung Squamous Cell Carcinoma CPZ 0.09 0.01 blup 80 0.03 4.4e-04 -1.5 11.8 3.7e-32 -0.54 0.02 0.52 TRUE
82 The Cancer Genome Atlas Prostate Adenocarcinoma C4orf23 0.06 0.03 enet 11 0.03 3.1e-04 -7.5 -5.2 2.2e-07 0.04 0.00 0.99 FALSE
83 The Cancer Genome Atlas Prostate Adenocarcinoma CPZ 0.10 0.12 lasso 4 0.13 3.1e-13 9.4 9.4 3.7e-21 -0.49 1.00 0.00 FALSE
84 The Cancer Genome Atlas Prostate Adenocarcinoma GRPEL1 0.05 0.04 blup 52 0.05 9.0e-06 -4.4 -6.1 1.0e-09 0.06 0.08 0.91 FALSE
85 The Cancer Genome Atlas Thyroid Carcinoma C4orf23 0.15 0.11 blup 90 0.13 5.2e-13 -5.6 -5.5 4.8e-08 0.06 0.03 0.97 FALSE
86 The Cancer Genome Atlas Thyroid Carcinoma SLC2A9 0.10 0.05 blup 208 0.05 2.7e-05 -5.8 -6.2 4.5e-10 0.02 0.02 0.96 FALSE
87 The Cancer Genome Atlas Thyroid Carcinoma TBC1D14 0.06 0.04 lasso 2 0.05 7.6e-06 -5.3 5.9 3.9e-09 -0.03 0.04 0.94 FALSE
88 The Cancer Genome Atlas Thyroid Carcinoma WDR1 0.12 0.05 blup 111 0.06 2.4e-06 -4.1 5.6 1.8e-08 -0.03 0.15 0.85 FALSE