Best TWAS P=2.45e-10 · Best GWAS P=1.97e-11 conditioned to 0.00588
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | RP11-819C21.1 | 0.18 | 0.08 | enet | 2 | 0.02 | 8.8e-02 | -6.3 | 5.4 | 6.5e-08 | -0.76 | 0.05 | 0.60 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | RP11-819C21.1 | 0.15 | -0.01 | lasso | 1 | -0.01 | 7.0e-01 | -6.3 | 6.3 | 3.9e-10 | -0.80 | 0.04 | 0.21 | FALSE |
| 3 | GTEx | Muscle Skeletal | CWF19L2 | 0.08 | 0.05 | lasso | 3 | 0.05 | 1.1e-05 | -6.3 | -6.3 | 2.4e-10 | 0.80 | 0.02 | 0.98 | TRUE |
| 4 | GTEx | Testis | CWF19L2 | 0.20 | 0.09 | lasso | 6 | 0.09 | 1.0e-04 | -6.3 | -5.7 | 1.3e-08 | 0.72 | 0.10 | 0.84 | FALSE |
| 5 | The Cancer Genome Atlas | Colon Adenocarcinoma | CWF19L2 | 0.11 | 0.01 | blup | 105 | 0.02 | 3.0e-02 | 2.0 | -5.7 | 9.6e-09 | 0.62 | 0.01 | 0.02 | FALSE |
| 6 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CWF19L2 | 0.05 | 0.00 | blup | 106 | 0.01 | 3.4e-02 | -2.6 | -5.2 | 2.3e-07 | 0.71 | 0.00 | 0.02 | FALSE |