[Hub]/) : Traits : Heel bone mineral density (BMD) T-score, automated (left) : ← →

chr11:59,239,839-62,326,265

Best TWAS P=1.09e-08 · Best GWAS P=2.51e-09 conditioned to 0.369

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta MS4A7 0.15 0.02 enet 28 0.04 3.6e-03 4.1 -5.6 2.6e-08 -0.18 0.64 0.12 FALSE
2 GTEx Colon Transverse FADS2 0.18 0.11 lasso 7 0.16 8.1e-08 4.4 5.4 6.1e-08 -0.01 0.01 0.97 TRUE
3 GTEx Nerve Tibial MS4A14 0.26 0.25 lasso 7 0.24 1.2e-16 4.8 -5.4 6.4e-08 -0.17 0.68 0.32 FALSE
4 GTEx Whole Blood MS4A6A 0.05 0.03 lasso 5 0.03 6.1e-04 -5.2 5.4 5.5e-08 0.70 0.19 0.76 FALSE
5 GTEx Whole Blood MS4A14 0.08 0.01 lasso 4 0.02 2.9e-03 3.8 -5.3 1.3e-07 -0.19 0.44 0.18 FALSE
6 YFS Blood FADS1 0.11 0.08 lasso 8 0.09 6.1e-29 4.4 5.3 1.2e-07 -0.01 0.01 0.96 FALSE
7 YFS Blood MS4A6A 0.13 0.10 enet 33 0.11 2.5e-35 -5.1 5.6 1.9e-08 0.52 0.28 0.72 FALSE
8 The Cancer Genome Atlas Breast Invasive Carcinoma MS4A4A 0.04 0.03 blup 79 0.04 7.2e-08 5.4 5.6 2.1e-08 0.80 0.03 0.97 FALSE
9 The Cancer Genome Atlas Glioblastoma Multiforme MS4A14 0.44 0.38 blup 86 0.42 3.6e-14 3.8 -5.4 5.8e-08 -0.19 0.03 0.97 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MS4A7 0.02 0.00 blup 77 0.00 1.2e-01 -3.5 5.3 1.0e-07 0.39 0.04 0.48 FALSE
11 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma MS4A6A 0.05 0.01 enet 10 0.03 6.6e-03 5.4 5.6 2.5e-08 0.85 0.01 0.63 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma MS4A2 0.04 0.04 blup 55 0.04 8.2e-04 -5.1 -5.7 1.1e-08 -0.79 0.02 0.93 TRUE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors MS4A4A 0.16 0.02 blup 78 0.03 2.7e-02 5.4 5.2 2.2e-07 0.77 0.01 0.62 FALSE