[Hub]/) : Traits : Trunk predicted mass :

chr19:9,637,688-12,921,186

Best TWAS P=4.46e-19 · Best GWAS P=7.06e-19 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAVER1 0.06 0.03 bslmm 388 0.04 2.5e-05 -2.0 -5.7 1.0e-08 -0.48 0.21 0.34 FALSE
2 CommonMind Brain Pre-frontal Cortex S1PR2 0.07 0.02 bslmm 369 0.03 5.3e-05 -5.3 6.3 2.7e-10 0.31 0.32 0.14 FALSE
3 CommonMind Brain Pre-frontal Cortex ZNF788 0.08 0.05 lasso 6 0.04 5.9e-06 5.6 5.5 3.4e-08 -0.09 0.01 0.99 TRUE
4 GTEx Adipose Subcutaneous EPOR 0.11 0.04 lasso 7 0.04 3.8e-04 4.8 5.5 5.1e-08 0.39 0.01 0.98 FALSE
5 GTEx Esophagus Mucosa SLC44A2 0.13 0.00 lasso 6 0.02 1.4e-02 5.1 -6.3 2.2e-10 -0.46 0.06 0.62 FALSE
6 GTEx Esophagus Mucosa ILF3-AS1 0.11 0.00 lasso 4 0.00 2.5e-01 8.9 -7.6 4.1e-14 -0.77 0.02 0.89 FALSE
7 GTEx Muscle Skeletal SLC44A2 0.19 0.18 lasso 5 0.19 5.1e-18 7.1 7.7 1.6e-14 0.79 0.82 0.18 FALSE
8 GTEx Nerve Tibial ILF3-AS1 0.14 0.04 lasso 3 0.08 3.8e-06 8.8 -7.7 2.0e-14 -0.77 0.01 0.98 FALSE
9 GTEx Skin Sun Exposed Lower leg SMARCA4 0.15 0.10 enet 25 0.15 1.4e-12 3.4 -6.1 1.0e-09 -0.61 1.00 0.00 FALSE
10 GTEx Testis PDE4A 0.20 0.02 enet 39 0.04 6.4e-03 5.2 6.2 5.5e-10 0.06 0.06 0.04 TRUE
11 GTEx Vagina CTD-2369P2.2 0.50 -0.01 lasso 9 0.01 2.0e-01 5.6 5.6 1.8e-08 0.01 0.22 0.11 TRUE
12 GTEx Whole Blood SLC44A2 0.11 0.01 enet 30 0.02 5.2e-03 7.0 -5.2 2.4e-07 -0.60 0.03 0.89 FALSE
13 GTEx Whole Blood CTD-2369P2.8 0.12 0.11 lasso 3 0.10 9.2e-10 5.9 6.4 1.6e-10 0.06 1.00 0.00 TRUE
14 NTR Blood SMARCA4 0.07 0.06 lasso 11 0.06 9.0e-18 5.5 -6.0 1.5e-09 -0.43 1.00 0.00 FALSE
15 ROSMAP Brain Pre-frontal Cortex AP1M2 0.09 0.01 lasso 5 0.03 3.3e-05 5.1 5.3 1.0e-07 0.37 0.13 0.19 FALSE
16 ROSMAP Brain Pre-frontal Cortex ILF3-AS1 0.15 0.04 bslmm 354 0.18 7.1e-22 -1.3 -6.0 2.5e-09 -0.61 0.05 0.95 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma S1PR2 0.02 0.00 blup 32 0.01 1.5e-02 -6.1 6.3 3.7e-10 0.04 0.00 0.65 TRUE
18 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FDX1L 0.06 0.02 lasso 3 0.04 2.4e-05 -4.4 -5.8 6.5e-09 -0.04 0.23 0.08 TRUE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma LOC147727 0.13 0.02 blup 28 0.04 7.2e-05 8.8 -7.0 3.2e-12 -0.76 0.01 0.90 FALSE
20 The Cancer Genome Atlas Brain Lower Grade Glioma FDX1L 0.06 0.00 blup 53 0.02 5.1e-03 -4.4 -5.7 1.5e-08 0.05 0.01 0.04 FALSE
21 The Cancer Genome Atlas Brain Lower Grade Glioma LOC147727 0.07 0.02 lasso 2 0.02 5.4e-03 8.9 -8.9 4.5e-19 -0.99 0.01 0.87 TRUE
22 The Cancer Genome Atlas Thyroid Carcinoma SLC44A2 0.32 0.22 enet 14 0.25 3.8e-24 8.2 6.6 5.2e-11 0.85 0.64 0.36 FALSE