Best TWAS P=6.27e-09 · Best GWAS P=5.51e-08 conditioned to 0.136
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | RABEP1 | 0.19 | -0.01 | lasso | 13 | 0.00 | 4.2e-01 | 4.6 | -5.3 | 1.4e-07 | -0.82 | 0.03 | 0.79 | FALSE |
| 2 | GTEx | Esophagus Muscularis | RABEP1 | 0.13 | 0.09 | lasso | 10 | 0.10 | 2.1e-06 | 5.4 | -5.2 | 2.3e-07 | -0.94 | 0.02 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | RPAIN | 0.06 | 0.06 | lasso | 3 | 0.06 | 3.1e-08 | 5.4 | -5.6 | 2.1e-08 | -0.98 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Glioblastoma Multiforme | NUP88 | 0.12 | 0.07 | enet | 12 | 0.09 | 1.2e-03 | 4.6 | -5.5 | 4.0e-08 | -0.78 | 0.02 | 0.67 | FALSE |
| 5 | The Cancer Genome Atlas | Glioblastoma Multiforme | RABEP1 | 0.23 | 0.13 | blup | 79 | 0.15 | 3.4e-05 | 4.7 | -5.8 | 6.3e-09 | -0.77 | 0.05 | 0.85 | TRUE |