Best TWAS P=1.49e-14 · Best GWAS P=2.66e-16 conditioned to 0.0208
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NEBL | 0.07 | 0.01 | blup | 662 | 0.03 | 9.7e-05 | -3.9 | -5.2 | 2.4e-07 | -0.03 | 0.76 | 0.01 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 8.0e-04 | 7.5 | -7.7 | 1.5e-14 | -0.94 | 0.01 | 0.99 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 6.1e-02 | 5.9 | 6.7 | 2.9e-11 | 0.90 | 0.09 | 0.82 | FALSE |
| 4 | GTEx | Spleen | MLLT10 | 0.16 | 0.02 | lasso | 7 | 0.02 | 1.0e-01 | 5.9 | -7.0 | 2.0e-12 | -0.92 | 0.02 | 0.67 | FALSE |