Best TWAS P=1.82e-08 · Best GWAS P=7.32e-11 conditioned to 3.23e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FAM114A2 | 0.28 | 0.39 | lasso | 9 | 0.41 | 1.8e-53 | -5.0 | 5.3 | 9.0e-08 | 0.22 | 0.97 | 0.03 | FALSE |
| 2 | NTR | Blood | FAM114A2 | 0.04 | 0.03 | lasso | 10 | 0.02 | 8.9e-08 | -5.0 | 5.2 | 1.8e-07 | 0.18 | 0.97 | 0.03 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | FAM114A2 | 0.05 | 0.06 | lasso | 6 | 0.05 | 6.3e-07 | -5.6 | 5.6 | 1.8e-08 | 0.29 | 0.75 | 0.24 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | FAM114A2 | 0.07 | 0.06 | blup | 56 | 0.06 | 1.5e-03 | -5.0 | -5.3 | 1.5e-07 | -0.15 | 0.03 | 0.57 | FALSE |