Best TWAS P=7.95e-17 · Best GWAS P=8.11e-26 conditioned to 6.28e-14
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TMEM196 | 0.08 | 0.01 | bslmm | 554 | 0.02 | 1.5e-03 | 6.0 | 5.8 | 8.8e-09 | 0.46 | 0.12 | 0.47 | FALSE |
| 2 | GTEx | Nerve Tibial | TWISTNB | 0.20 | 0.01 | enet | 13 | 0.07 | 9.4e-06 | 4.7 | 6.0 | 2.7e-09 | 0.34 | 0.35 | 0.09 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | TWIST1 | 0.09 | 0.02 | blup | 618 | 0.02 | 8.5e-04 | -5.4 | -8.3 | 7.9e-17 | -0.19 | 0.36 | 0.02 | TRUE |