[Hub]/) : Traits : Nervous feelings : ← →

chr3:49,598,064-51,234,774

Best TWAS P=9.61e-08 · Best GWAS P=7.83e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts SEMA3B-AS1 0.15 0.01 enet 3 0.00 3.9e-01 4.8 5.1 3.1e-07 0.86 0.02 0.92 FALSE
2 GTEx Esophagus Gastroesophageal Junction HYAL1 0.30 0.13 lasso 9 0.10 2.1e-04 5.1 5.2 2.3e-07 0.88 0.01 0.96 FALSE
3 GTEx Esophagus Muscularis HYAL1 0.11 0.08 lasso 5 0.05 3.3e-04 5.1 5.2 1.7e-07 0.90 0.01 0.99 FALSE
4 GTEx Muscle Skeletal HYAL1 0.08 0.08 lasso 3 0.06 7.6e-07 5.2 5.2 1.6e-07 0.92 0.01 0.99 FALSE
5 GTEx Muscle Skeletal SEMA3B-AS1 0.17 0.01 lasso 7 0.02 8.3e-03 5.2 5.3 1.5e-07 0.77 0.03 0.93 FALSE
6 GTEx Nerve Tibial U73166.2 0.07 0.03 lasso 3 0.03 2.8e-03 5.2 -5.3 9.6e-08 -0.96 0.01 0.98 TRUE
7 GTEx Thyroid U73166.2 0.05 0.02 enet 6 0.01 5.9e-02 5.4 -5.3 1.0e-07 -0.98 0.01 0.96 FALSE
8 METSIM Adipose CYB561D2 0.09 0.08 lasso 5 0.07 3.8e-10 5.1 -5.3 1.1e-07 -0.85 0.02 0.98 FALSE
9 ROSMAP Brain Pre-frontal Cortex CACNA2D2 0.05 0.02 lasso 3 0.02 3.6e-03 5.2 -5.3 1.4e-07 -0.92 0.01 0.98 FALSE
10 ROSMAP Brain Pre-frontal Cortex SEMA3B 0.05 0.03 lasso 6 0.02 8.3e-04 5.1 5.3 1.5e-07 0.88 0.01 0.99 FALSE