[Hub]/) : Traits : Triglycerides : ← →

chr4:86,819,377-89,140,356

Best TWAS P=5.3e-10 · Best GWAS P=3.9e-11 conditioned to 0.0134

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SPARCL1	0.08	0.02	bslmm	512	0.04	1.2e-05	-6.3	-5.3	1.1e-07	0.62	0.04	0.94	FALSE
2	GTEx	Adrenal Gland	PTPN13	0.15	0.05	lasso	3	0.06	2.8e-03	3.2	-5.1	3.0e-07	0.35	0.10	0.33	TRUE
3	GTEx	Artery Tibial	AFF1	0.10	0.06	lasso	5	0.06	2.4e-05	-6.4	-5.9	2.9e-09	0.93	0.01	0.98	FALSE
4	GTEx	Brain Cerebellar Hemisphere	AFF1	0.52	0.14	enet	47	0.27	1.4e-07	-6.4	-5.1	2.9e-07	0.59	0.02	0.97	FALSE
5	GTEx	Brain Cerebellum	AFF1	0.30	0.09	enet	15	0.26	2.5e-08	-3.3	-5.9	4.0e-09	0.67	0.03	0.95	FALSE
6	GTEx	Breast Mammary Tissue	HSD17B11	0.27	0.01	enet	40	0.03	8.1e-03	5.6	5.5	3.9e-08	-0.30	0.11	0.10	FALSE
7	GTEx	Breast Mammary Tissue	RP11-529H2.2	0.22	0.07	enet	9	0.06	6.3e-04	5.6	6.2	5.3e-10	-0.45	0.30	0.24	TRUE
8	GTEx	Breast Mammary Tissue (Female)	HSD17B11	0.14	-0.01	lasso	2	0.01	2.1e-01	4.8	5.5	3.3e-08	-0.33	0.04	0.08	FALSE
9	GTEx	Breast Mammary Tissue (Female)	RP11-529H2.2	0.07	0.03	lasso	1	-0.01	8.0e-01	5.3	5.3	8.9e-08	-0.31	0.04	0.08	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	RP11-397E7.4	0.17	0.01	lasso	10	0.02	7.0e-02	4.3	-5.4	5.2e-08	0.42	0.15	0.05	FALSE
11	GTEx	Esophagus Mucosa	HSD17B11	0.09	0.04	lasso	6	0.07	2.3e-05	5.6	5.7	1.1e-08	-0.48	0.51	0.17	FALSE
12	GTEx	Esophagus Mucosa	RP11-529H2.2	0.12	0.00	lasso	7	0.00	1.6e-01	5.6	5.3	1.1e-07	-0.45	0.06	0.36	FALSE
13	GTEx	Esophagus Muscularis	HSD17B13	0.12	0.04	lasso	5	0.02	1.9e-02	-5.7	5.6	1.9e-08	-0.47	0.06	0.29	FALSE
14	GTEx	Lung	HSD17B13	0.07	0.01	lasso	4	0.00	1.8e-01	5.6	-5.6	1.8e-08	0.33	0.23	0.11	FALSE
15	GTEx	Skin Sun Exposed Lower leg	HSD17B13	0.11	0.09	lasso	5	0.08	2.2e-07	5.4	-5.4	6.2e-08	0.33	0.62	0.37	FALSE
16	GTEx	Thyroid	RP11-529H2.2	0.10	0.06	lasso	5	0.04	4.4e-04	5.6	5.7	1.2e-08	-0.44	0.52	0.31	FALSE
17	METSIM	Adipose	AFF1	0.06	0.05	lasso	11	0.06	8.1e-09	4.7	-6.1	9.7e-10	0.69	0.07	0.93	FALSE
18	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	HSD17B11	0.05	0.02	enet	9	0.04	2.6e-05	-2.3	5.5	4.3e-08	-0.29	0.02	0.79	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	HSD17B13	0.05	0.07	enet	8	0.07	5.4e-09	5.3	-5.3	1.2e-07	0.21	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	HSD17B11	0.06	0.02	blup	51	0.05	2.2e-04	5.6	5.4	7.4e-08	-0.28	0.01	0.82	FALSE