[Hub]/) : Traits : Irritable Bowel Disease (IBD) : ← →

chr1:7,314,655-8,738,937

Best TWAS P=7.44e-14 · Best GWAS P=2.21e-15 conditioned to 0.00408

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PARK7 0.05 0.00 bslmm 423 0.01 1.2e-02 -7.1 6.9 5.0e-12 -0.63 0.06 0.68 FALSE
2 GTEx Skin Sun Exposed Lower leg PARK7 0.13 0.06 lasso 8 0.09 3.1e-08 4.1 -7.0 1.8e-12 0.71 0.28 0.70 FALSE
3 GTEx Thyroid PARK7 0.08 0.01 lasso 6 0.02 2.3e-02 4.0 -5.9 2.9e-09 0.60 0.06 0.76 FALSE
4 NTR Blood PARK7 0.02 0.01 lasso 3 0.01 1.4e-05 -7.1 -7.5 7.6e-14 0.87 0.04 0.96 TRUE
5 YFS Blood PARK7 0.08 0.11 lasso 6 0.11 4.4e-34 -7.1 -7.1 9.4e-13 0.84 0.63 0.37 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma ERRFI1 0.01 0.01 blup 27 0.00 4.3e-02 -7.1 7.5 7.4e-14 -0.88 0.01 0.83 FALSE
7 The Cancer Genome Atlas Breast Invasive Carcinoma PARK7 0.02 0.01 blup 36 0.02 2.1e-04 -7.2 -6.8 1.5e-11 0.74 0.01 0.92 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PARK7 0.03 0.03 enet 3 0.02 1.3e-03 -7.2 -7.0 3.2e-12 0.88 0.00 0.94 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma PARK7 0.03 0.03 lasso 1 0.02 5.0e-03 -7.1 -7.1 1.3e-12 0.84 0.01 0.82 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma PARK7 0.04 0.03 blup 36 0.03 4.9e-04 -7.2 -6.9 4.0e-12 0.80 0.01 0.96 FALSE
11 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma PARK7 0.22 0.00 blup 35 0.03 2.2e-02 -7.2 -6.1 1.3e-09 0.63 0.00 0.52 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma PARK7 0.09 0.05 lasso 4 0.07 3.4e-08 4.2 -6.7 1.8e-11 0.67 0.06 0.94 FALSE