[Hub]/) : Traits : Heel T-Score :

chr2:99,082,938-100,709,384

Best TWAS P=5.96e-10 · Best GWAS P=2.26e-10 conditioned to 0.0123

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland MITD1 0.09 0.01 lasso 10 0.01 2.0e-01 4.7 5.2 2.3e-07 0.70 0.05 0.47 FALSE
2 GTEx Adrenal Gland RP11-527J8.1 0.20 0.08 lasso 5 0.12 6.4e-05 4.7 6.2 6.0e-10 0.76 0.01 0.97 TRUE
3 GTEx Breast Mammary Tissue LYG1 0.11 0.16 lasso 6 0.14 9.1e-08 6.3 6.0 2.4e-09 0.99 0.01 0.99 FALSE
4 GTEx Breast Mammary Tissue (Male) LYG1 0.16 0.13 lasso 7 0.10 2.4e-03 6.0 6.0 2.5e-09 0.98 0.01 0.94 FALSE
5 GTEx Colon Sigmoid LYG1 0.21 0.13 lasso 5 0.16 3.4e-06 5.8 5.3 1.1e-07 0.90 0.05 0.88 FALSE
6 GTEx Esophagus Mucosa LYG1 0.16 0.05 enet 20 0.08 5.9e-06 4.0 5.6 1.8e-08 0.78 0.02 0.98 FALSE
7 GTEx Nerve Tibial LYG1 0.10 0.12 lasso 2 0.14 6.2e-10 5.8 5.2 1.7e-07 0.90 0.04 0.96 FALSE