Best TWAS P=1.18e-08 · Best GWAS P=8.37e-07 conditioned to 0.00627
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | FOXO6 | 0.35 | 0.33 | enet | 21 | 0.36 | 1.2e-11 | 4.7 | 5.6 | 2.2e-08 | 0.93 | 0.01 | 0.97 | FALSE |
| 2 | GTEx | Nerve Tibial | SCMH1 | 0.16 | 0.03 | enet | 24 | 0.07 | 1.6e-05 | 4.7 | -5.7 | 1.2e-08 | -0.43 | 0.03 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | SCMH1 | 0.07 | 0.08 | blup | 97 | 0.07 | 2.5e-07 | 4.7 | -5.5 | 3.1e-08 | -0.42 | 0.02 | 0.96 | FALSE |