Best TWAS P=3.67e-08 · Best GWAS P=1.05e-07 conditioned to 0.319
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | MYOZ1 | 0.04 | 0.01 | blup | 235 | 0.02 | 0.0026 | 4.6 | -5.4 | 6.0e-08 | -0.65 | 0.08 | 0.78 | FALSE |
| 2 | YFS | Blood | FUT11 | 0.02 | 0.00 | bslmm | 231 | 0.01 | 0.0020 | -3.6 | 5.3 | 1.2e-07 | 0.42 | 0.25 | 0.15 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | SEC24C | 0.02 | 0.01 | enet | 4 | 0.01 | 0.0085 | 4.7 | -5.3 | 9.4e-08 | -0.78 | 0.01 | 0.67 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NDST2 | 0.03 | 0.02 | blup | 37 | 0.02 | 0.0033 | 5.1 | 5.5 | 3.7e-08 | 0.88 | 0.03 | 0.89 | TRUE |