[Hub]/) : Traits : Alzheimer’s Disease (in mother) : ←

chr19:44,190,626-46,190,531

Best TWAS P=6.44e-68 · Best GWAS P=5.51e-89 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	CLPTM1	0.11	0.09	enet	10	0.08	2.0e-10	3.41	-5.6	2.2e-08	-0.01	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	PVRL2	0.10	0.03	lasso	2	0.03	9.2e-05	-1.44	-7.5	6.9e-14	-0.07	0.68	0.03	TRUE
3	GTEx	Adipose Subcutaneous	CEACAM19	0.13	0.11	enet	9	0.12	4.6e-10	5.49	5.2	1.9e-07	-0.11	0.98	0.00	FALSE
4	GTEx	Adipose Visceral Omentum	ZNF285	0.17	0.05	enet	20	0.07	1.3e-04	-2.45	-12.9	7.7e-38	0.17	0.39	0.15	FALSE
5	GTEx	Cells Transformed fibroblasts	CEACAM19	0.35	0.26	lasso	2	0.28	8.7e-21	5.49	5.2	1.7e-07	-0.12	1.00	0.00	TRUE
6	GTEx	Liver	PVRL2	0.29	0.24	lasso	4	0.21	1.4e-06	-5.66	5.5	3.1e-08	0.12	0.21	0.05	TRUE
7	GTEx	Skin Not Sun Exposed Suprapubic	ZNF229	0.28	0.09	enet	58	0.08	2.2e-05	-2.58	-13.1	2.0e-39	-0.03	0.17	0.16	TRUE
8	GTEx	Stomach	BCAM	0.33	0.00	enet	3	0.01	9.6e-02	3.08	-5.9	3.0e-09	0.09	0.07	0.07	FALSE
9	GTEx	Thyroid	CEACAM19	0.34	0.28	enet	26	0.30	9.9e-24	5.49	8.9	3.4e-19	-0.18	1.00	0.00	TRUE
10	YFS	Blood	TOMM40	0.04	0.00	bslmm	371	0.01	2.6e-04	-9.22	8.8	1.0e-18	0.09	0.03	0.36	TRUE
11	The Cancer Genome Atlas	Glioblastoma Multiforme	GEMIN7	0.24	0.05	lasso	3	0.13	9.6e-05	7.08	6.5	9.2e-11	-0.14	0.01	0.70	TRUE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CEACAM16	0.04	0.00	enet	6	0.02	1.4e-03	-4.56	6.0	2.2e-09	-0.17	0.03	0.06	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	APOC1P1	0.05	0.03	blup	37	0.03	5.2e-04	-10.77	16.3	4.6e-60	0.53	0.14	0.20	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PVR	0.08	0.10	lasso	4	0.09	9.8e-11	-5.79	-5.3	9.3e-08	0.06	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TOMM40	0.04	0.03	lasso	2	0.02	1.4e-03	-17.48	17.4	6.4e-68	0.65	0.12	0.09	TRUE
16	The Cancer Genome Atlas	Brain Lower Grade Glioma	APOC4	0.06	0.03	blup	34	0.04	8.4e-06	0.41	6.5	7.8e-11	0.14	0.70	0.02	TRUE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	CEACAM19	0.08	0.05	lasso	4	0.05	3.3e-06	5.49	5.4	5.7e-08	-0.13	0.01	0.98	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	NKPD1	0.03	0.00	blup	37	0.01	4.5e-02	4.76	-6.0	2.5e-09	0.12	0.02	0.47	TRUE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	APOC1	0.05	0.00	blup	47	0.01	4.3e-02	0.34	-12.8	1.6e-37	0.32	0.01	0.06	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	APOE	0.06	0.00	blup	49	0.01	4.5e-02	0.34	-9.7	3.3e-22	0.19	0.02	0.06	FALSE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	APOC2	0.18	0.12	enet	14	0.13	5.2e-06	0.41	8.8	1.1e-18	-0.11	0.65	0.03	TRUE
22	The Cancer Genome Atlas	Prostate Adenocarcinoma	CEACAM19	0.15	0.08	lasso	3	0.07	4.0e-08	5.49	5.4	6.0e-08	-0.12	0.01	0.99	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	TOMM40	0.08	0.07	enet	13	0.07	2.2e-07	-17.48	10.9	9.8e-28	0.67	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Soft Tissue Sarcoma	APOC4	0.13	0.10	blup	34	0.13	3.2e-08	4.95	8.6	5.7e-18	-0.03	0.96	0.00	TRUE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	APOC4	0.07	0.09	lasso	2	0.09	3.2e-07	4.65	5.2	2.4e-07	-0.03	0.78	0.01	TRUE
26	The Cancer Genome Atlas	Testicular Germ Cell Tumors	APOC1P1	0.14	0.01	blup	36	0.06	3.8e-03	-1.44	10.7	1.3e-26	0.51	0.01	0.07	TRUE
27	The Cancer Genome Atlas	Thyroid Carcinoma	CEACAM19	0.26	0.13	lasso	3	0.14	4.0e-13	5.49	5.2	2.1e-07	-0.14	0.01	0.99	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	PVRL2	0.09	0.05	blup	55	0.03	4.6e-04	-1.37	-8.2	3.3e-16	0.45	0.48	0.05	TRUE
29	The Cancer Genome Atlas	Thyroid Carcinoma	TOMM40	0.05	0.07	lasso	3	0.06	1.1e-06	-15.33	14.7	9.2e-49	0.62	0.89	0.01	FALSE
30	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	APOC2	0.20	0.14	enet	10	0.14	7.9e-05	1.93	-6.9	4.2e-12	0.12	0.15	0.05	FALSE